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Graduate Course Proposal Form Submission Detail - BME6001

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Current Status: Approved by SCNS - 2016-07-01
Campus: Tampa
Submission Type: New
Course Change Information (for course changes only):
Comments: Elective for Biomed Eng. To GC. Why does this support the BS? Accel Program? Emailed 4/13/16. Elective for MSBME or BSChE. Not Accel Program. Cleared. GC Approved To USF Sys 5/18/16; to SCNS after 5/25/16. SCNS approved eff 7/1/16

  1. Department and Contact Information

    Tracking Number Date & Time Submitted
    5366 2016-01-12
    Department College Budget Account Number
    Chemical Engineering EN 2107-0000
    Contact Person Phone Email
    Dr. Babu Joseph 9740692

  2. Course Information

    Prefix Number Full Title
    BME 6001 Biomedical Engineering II

    Is the course title variable? N
    Is a permit required for registration? N
    Are the credit hours variable? N
    Is this course repeatable? N
    If repeatable, how many times? 0

    Credit Hours Section Type Grading Option
    3 C - Class Lecture (Primarily) R - Regular
    Abbreviated Title (30 characters maximum)
    Biomedical Engineering II
    Course Online? Percentage Online
    C - Face-to-face (0% online) 0




    Course Description

    This course will address a wide range of fundamental topics in biomedical engineering, focusing on the application of engineering fundamentals to the analysis of the human biomedical system.

  3. Justification

    A. Please briefly explain why it is necessary and/or desirable to add this course.

    Needed to compete with national trends

    B. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service?

    The enrollment in this course when offered as a Special Topics course was around 20.

    C. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times?

    Yes, 2 times

    D. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.)

    PhD in Biomedical, Chemical or a closely related field is required.

  4. Other Course Information

    A. Objectives

    1. Learn to apply systems concepts to the human body

    2. Study basic principles of biomechanics

    3. Learn about biomaterials and biocompatibility

    4. Study basics of cell transport

    5. Learn basics of biofluidics

    6. Basic concepts of sensing and signal transmission in the body

    7. Learn about medical imaging techniques

    B. Learning Outcomes

    After completing this course, students will be able to:

     Understand that the laws of thermodynamics apply to human subjects

     Describe basic biomechanical parameters and the associated test procedures

     Understand how tissue architecture relates to observed biomechanical properties

     Describe the basic requirements of implant devices

     Understand the basics of biocompatibility (including blood compatibility, toxicology,

    carcinogenesis, etc.)

     Describe the basic wound healing process, including the inflammatory and blood clotting


     Describe the requirements and challenges of designing a new biomaterial

     Describe the basics of kidney function and how an artificial kidney works

     Describe the basics of how materials move into/out of cells

     Describe the basics of blood and blood flow

     Understand the basics of the human sensory system and its general behavior

     Describe the challenges in measuring pain

     Understand how the sensory system plays a role in biomedical product development

     Describe the challenges in the development of artificial sensory systems

     Describe the basic features and underlying physics of medical imaging modalities

     Describe the basic types of data that would be associated with a human subject study

     Understand the basics of a clinical trial

     Display a general understanding of how the legal system can impact a biomedical engineer

     Describe what clinical engineering is and what a clinical engineer does

     Describe the basics of anthropometry and how it is applied

     Understand the basics of “junk science” and how it influences biomedical engineering

     Understand the role of medical and engineering ethics and how it influences biomedical


     Describe the basic features of biomedical product development and how it interacts with the

    regulatory environment

    C. Major Topics

    1. Mass and Energy Inventory concepts applied to the human body

    2. Biomechanics

    3. Biomaterials and biocompatibility

    4. Cell transport mechanisms

    5. Biofluidics

    6. Sensing and signal transmission

    7. Medical Imaging

    D. Textbooks

    Lecture notes will be provided on Canvas

    E. Course Readings, Online Resources, and Other Purchases

    Based on Lecture Notes

    F. Student Expectations/Requirements and Grading Policy

    Several in class tests will be given. Grading will be done using cluster analysis. There will be several project assignments as well. All grades will be counted without any drops.

    G. Assignments, Exams and Tests

    1‐3 Material and energy balances


    1) Evaluate suggested weight management (dietary) programs from a thermodynamics viewpoint

    2) Summarize an actual experimental procedure used to measure energy balance parameters on human


    Test #1

    4‐6 Biomechanics

    Anatomical description of the body; anthropometry

    Materials science review; soft tissue composition and biomechanics (including skin, tendons, ligaments,

    muscles, etc.); soft tissue implants; hard tissue composition and biomechanics; hard tissue implants.

    Skin care products, cosmetics, and related products.

    Project: evaluate a health and beauty product in terms of listed ingredients and the scientific soundness

    of all listed ingredients

    Project: evaluate two different kinds of total shoulder joint replacements (“anatomical” and “reverse”)

    Test #2

    7‐9 Biomaterials and biocompatibility

    Basic biomaterials (ceramics, metals, polymers, etc.) biocompatibility; blood compatible materials (will

    also include toxicology basics)

    Project: Summarize a test procedure on some aspect of biocompatibility

    Project: Paper on why the life expectancy of orthopedic implants is limited

    Test #3

    10‐11 Cell transport, human and artificial kidneys

    Project: Summarize any technical advances that have occurred in the last 10‐15 years regarding artificial


    Project: Summarize one “novel” approach that is currently being researched or has been proposed to

    deliver drugs into living cells (“targeted drug delivery”)

    12‐13 BioFluid aspects: blood and the circulatory system

    Blood characteristics; blood flow; blood fractionation, pharmacodynamics.

    Project: Short report on the blood fractionation business

    Test #4

    14 “Sensor” aspects: neuroscience and environmental sensing

    Basics of nerves (focusing on sensory), dermal sensors, overview of other sensory systems

    How sensory processes play a role in biomedical product development

    Project: Simple sensory evaluation group project

    15‐16 Medical imaging

    Overview of: biomedical imaging (ultrasound, x‐ray, MRI, CT, etc.)

    Project: Summarize the health risks (if any) for all imaging modalities discussed.

    Test #5

    Special topics (address throughout the semester as time permits)

    A. The regulatory environment (FDA, medical devices, etc.)

    B. Biostatistics overview

    C. Product development issues

    D. Biomedical ethics

    E. Forensic engineering

    F. The legal system and how it can involve you

    G. Validating knowledge/”junk science”

    H. Health care systems; clinical engineering

    “Special topics” materials will be covered on tests as well.

    As noted above, there will be a number of projects during the semester. Point values for such projects will be

    H. Attendance Policy

    Course Attendance at First Class Meeting – Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation – Registration - 4.0101,

    Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (

    In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. It’s the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.

    I. Policy on Make-up Work

    Will use standard USF policy and guidelines

    J. Program This Course Supports

    MS and PhD in Biomedical Engineering and Chemical Engineering, BS in Chemical Engineering

  5. Course Concurrence Information

    Chemical Engineering and Mechanical Engineering

- if you have questions about any of these fields, please contact or