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Graduate Course Proposal Form Submission Detail - PHA6531

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Current Status: Approved by SCNS - 2016-08-02
Campus: Tampa
Submission Type: Change
Course Change Information (for course changes only): We would like to change the course title from "Basic Principles of Toxicology" to "Clinical Toxicology".
Comments: Elective for PharmD. To GC. Needs Revision - course desc too long. Emailed 5/5/16. Updated 5/18/16. Approved 5/18/16 To USF Sys 5/18/16. to SCNS after 5/25/16. Apprd eff 8/2/16

  1. Department and Contact Information

    Tracking Number Date & Time Submitted
    5334 2015-11-23
    Department College Budget Account Number
    Pharmacy - PharmD RX 84020
    Contact Person Phone Email
    Maj-Linda Selenica 8139745336

  2. Course Information

    Prefix Number Full Title
    PHA 6531 Basic Principles of Toxicology

    Is the course title variable? N
    Is a permit required for registration? N
    Are the credit hours variable? N
    Is this course repeatable?
    If repeatable, how many times? 1

    Credit Hours Section Type Grading Option
    2 C - Class Lecture (Primarily) R - Regular
    Abbreviated Title (30 characters maximum)
    Course Online? Percentage Online
    C - Face-to-face (0% online) 0



    Course Description

    Focus on the clinical principles of toxicology, and the potential health hazards associated with toxin exposure. Review the specialized areas of toxicology, emphasizing the importance of target organ and non-organ toxicity and patient management.

  3. Justification

    A. Please briefly explain why it is necessary and/or desirable to add this course.

    Offered as enrichment course (not part of program/concentration/certificate)

    B. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service?

    Students have expressed an interest in this elective.

    C. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times?


    D. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.)

    Master degree in any kind of life and biological sciences

  4. Other Course Information

    A. Objectives

    1. Define toxicology and toxicity

    2. Describe the different toxidromes

    3. Discuss the drug based toxins classification and their mechanism of action

    4. Discuss types of non-organ directed toxicity

    5. Discuss types of toxin responses in specific organs

    6. Describe the spectrum of toxic agents

    7. Understand the potential adverse effects resulting from human exposures to toxic agents

    8. Understand the initial diagnosis and management of poisoned patient

    9. Understand the antidotes in depth

    10. Discuss the analytic tools used for the qualitative and quantitative estimation of chemicals that may exert adverse effects on living organisms.

    B. Learning Outcomes

    • Understanding needs and utilize the principles of empathy, honesty, and integrity in providing a patient-centered care

    • Analyze epidemiologic and pharmacoeconomic data in order to provide population-based care

    • Manage a successful patient-centered practice

    • Manage available resources to ensure quality and cost-effective patient care

    • Collaboration with others on the health care team and an understanding of system-based practice

    • Collect, interpret, and evaluate pharmaceutical data in order to improve medication safety and reduce errors

    • Promote public awareness of health and disease to advance patient-based care

    • Demonstrate effective communication skills in a variety of circumstances and settings

    • Demonstrate knowledge and comprehension of principles of evidence-based medicine

    • Effectively use information systems and computer software to enhance delivery of pharmaceutical care

    • Provide pharmaceutical care ethically and compassionately

    • Carry our duties in accordance with legal and ethical professional guidelines

    • Maintain professional competence

    C. Major Topics

    1. Principles and vital Signs in clinical toxicology

    2. The Importance of case study practice in toxicology

    3. Drug – based toxicology

    4. Analgesic and anti-inflammatory toxins

    5. Cardiovascular toxins

    6. Substances of abuse and generic drugs toxicity

    7. Hepatic drugs and toxicity

    8. Clinical management of psychotropic medication

    9. Disaster preparedness

    10. Natural toxins

    11. Occupational and household Toxicology

    12. Dietary toxicology

    13. Pesticides and Metals

    14. Analytical and Forensic Toxicology

    D. Textbooks


    Goldfrank's Toxicologic Emergencies, 10e

    Robert S. Hoffman, Mary Ann Howland, Neal A. Lewin, Lewis S. Nelson, Lewis R. Goldfrank. ISBN-13: 978-0071801843 .*Available through Access Pharmacy


    • Casarett & Doull's Essentials of Toxicology, 2rd edition ISBN:9780071622400 by Curtis D. Klaassen and John B. Watkins, III.*Available through Access Pharmacy; eSources

    • Lippincott's Manual of Toxicology, Lippincott, ISBN: 9781451173307

    E. Course Readings, Online Resources, and Other Purchases

    F. Student Expectations/Requirements and Grading Policy

    Quizzes 2 x 25 points 50

    Assignments 2 x 70 points 140

    Case Studies 2 x 50 points 100

    Online live discussions 10 points

    Total 300

    G. Assignments, Exams and Tests

    Student performance will be judged on the following:

    1. Quizzes (Administered by Canvas)

    2. Case Study Activities (class participation)

    3. Assignments (Administered by Canvas)

    4. Canvas live discussions (Canvas)

    H. Attendance Policy

    Course Attendance at First Class Meeting – Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation – Registration - 4.0101,

    Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (

    In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. It’s the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.

    I. Policy on Make-up Work

    Policy regarding missed quizzes/exams and taking exams early:

    If a quiz is missed, it cannot be made up.

    J. Program This Course Supports

    Doctor of Pharmacy program

  5. Course Concurrence Information


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