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Graduate Course Proposal Form Submission Detail - CHM6036
Tracking Number - 4952

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Current Status: Approved by SCNS - 2014-11-01
Campus: Tampa
Submission Type: New
Course Change Information (for course changes only):
Comments: Biochemistry Elective; to chair. Approved 5/19/14. to USF Sys 5/20/14. to SCNS 5/28/14. Apprd eff 11/1/14

Detail Information

  1. Date & Time Submitted: 2014-02-17
  2. Department: Chemistry
  3. College: AS
  4. Budget Account Number: 121300
  5. Contact Person: Jianfeng Cai
  6. Phone: 8139749506
  7. Email:
  8. Prefix: CHM
  9. Number: 6036
  10. Full Title: Chemical Biology
  11. Credit Hours: 3
  12. Section Type: C - Class Lecture (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: Y
  15. Are the credit hours variable?: N
  16. Is this course repeatable?: Y
  17. If repeatable, how many times?: 1
  18. Abbreviated Title (30 characters maximum): Chem Biol
  19. Course Online?: C - Face-to-face (0% online)
  20. Percentage Online: 0
  21. Grading Option: R - Regular
  22. Prerequisites: BCH 3053 or BCH 4033
  23. Corequisites:
  24. Course Description: Current research directions in chemical biology. Topics include chemical and biosynthesis of peptides, proteins and nucleic acids, genetic and protein engineering, combinatorial chemistry, targeted probes and imaging, bioorthogonal reactions, etc.

  25. Please briefly explain why it is necessary and/or desirable to add this course: Needed for new program/concentration/certificate
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? Chemical Biology is the latest emerging field. Currently our department lacks of a course in deep chemical biology for advanced undergraduate. The course combines both start-of-the-art chemistry and biological techniques, which educate students with a broad range of interdisciplinary knowledges.
  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times? Yes, 2 times
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) A Doctorate degree in Chemistry represent the required qualifications.
  29. Objectives: Possess an understanding of several areas of current Research in chemical biology, including the following: 1.Methods to control transcription/translation using small Molecules. 2. Methods to construct proteins containing modified amino acids, both chemically and biochemically. 3. Methods to screen for peptidomimetics with novel bioactivities. 4. Methods to prepared nucleic acids, both chemically and biochemically. 5. Methods for site-specific labeling of proteins or nucleic acids.
  30. Learning Outcomes: Students will be able to:

    • Gain experience in critical reading and evaluation of data in research articles in chemical biology

    • Learn central concepts in molecular biology, biology, and genetics that are Important for understanding several areas in chemical biology

    • Learning latest development in chemical biology including chemical and biochemical modification and manipulation of proteins and nucleic acids.

  31. Major Topics: The major course topics covered include unnatural peptidomimetics, chemical and biosynthesis of peptides and proteins, in vitro incorporation of unnatural amino acids into proteins, chemical and biosynthesis of nucleic acids, genetic engineering and protein engineering, aptamers, combinatorial chemistry, targeted probes and imaging, bioorthogonal reactions, protein-protein interactions, protein-DNA interactions, etc.
  32. Textbooks: This course will not require a course textbook, as the instructor already developed a comprehensive teaching materials. Meanwhile, latest papers in the field of chemical biology will be distributed and discussed in classes.
  33. Course Readings, Online Resources, and Other Purchases: N/A
  34. Student Expectations/Requirements and Grading Policy: Students enrolled in this course will be asked to give one oral presentation (30%), to write one research summary (20%), and to take one exam (50%).
  35. Assignments, Exams and Tests: Students enrolled in this course will be asked to give one oral presentation (30%), to write one research summary (20%), and to take one exam (50%).
  36. Attendance Policy: Course Attendance at First Class Meeting – Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation – Registration - 4.0101,

    Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (

    In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. It’s the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.

  37. Policy on Make-up Work: Incompletes

    The grade of “I” will be given only under exceptional circumstances, such as an extended illness certified by a practicing physician. To receive an incomplete, the student must have a passing grade on all completed work. Thus, students who are projected to fail the course cannot receive an incomplete. The student must complete all the requirements within one academic semester to remove the incomplete grade from their records, otherwise the “I” will automatically be replaced with an “IF” (or “IU”).

    Academic Dishonesty

    Cheating or disruptions in the classroom will not be tolerated. Any attempts to cheat on examinations will result in a zero for that exam, and possibly an “F” for the course, depending on the severity of the cheating. Students receiving an “F” as a result of academic misconduct will receive an “FF” on their record, and will be referred to the Dean’s Office for further action (including possible expulsion from the University).

  38. Program This Course Supports: Organic Chemistry and Biochemistry
  39. Course Concurrence Information: Organic Chemistry and Biochemistry

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