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Graduate Course Proposal Form Submission Detail - GMS6058
Tracking Number - 4882

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Current Status: Approved by SCNS - 2015-01-01
Campus: Tampa
Submission Type: New
Course Change Information (for course changes only):
Comments: for MNM Con in MSMS. Approved 3/4/14. To USF Sys 3/19. to SCNS 3/27/14. Appd eff 1/1/15

Detail Information

  1. Date & Time Submitted: 2014-01-14
  2. Department: Medical Sciences
  3. College: MD
  4. Budget Account Number: 610601
  5. Contact Person: Michael J. Barber
  6. Phone: 9749908
  7. Email:
  8. Prefix: GMS
  9. Number: 6058
  10. Full Title: Diet and Cancer
  11. Credit Hours: 3
  12. Section Type: C - Class Lecture (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: Y
  15. Are the credit hours variable?: N
  16. Is this course repeatable?: Y
  17. If repeatable, how many times?: 1
  18. Abbreviated Title (30 characters maximum): Diet and Cancer
  19. Course Online?: C - Face-to-face (0% online)
  20. Percentage Online: 0
  21. Grading Option: R - Regular
  22. Prerequisites: None
  23. Corequisites: None
  24. Course Description: This course is designed to focus on the linkage between diet and dietary factors and cancer and to explore the role of nutritional interventions as part of novel therapies for modern approaches to cancer treatment.

  25. Please briefly explain why it is necessary and/or desirable to add this course: Replacing Selected Topics with Permanent number; already listed in program
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? Metabolic Nutritional Medicine represents a new and evolving discipline in the medical sciences that deals with an integrative and functional medicine approach to healthcare and disease prevention The discipline combines evidence based medicine with new approaches to therapeutics and patient wellness. Nutrition and metabolism represent a critical approaches to understanding and controlling diseases such as obesity and cancer. The Metabolic Nutritional Medicine concentration currently has 119 registered students and approx 9 registered for the first course offering
  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times? Yes, 1 time
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) All the instructors in the course are M.D., D.O. or Ph.D. or equivalent trained faculty.
  29. Objectives: The course objectives include:

    Providing a detailed examination of selected case studies that feature nutritional interventions in integrative cancer therapy.

    Compare and contrast the properties of botanical supplements and their emerging roles in nutrition and gene expression.

    Define and discuss the role of dietary stress and compare and contrast the foods that support major metabolic functions and influence cancer progression.

    Examine the roles of fruits and vegetables in cancer prevention.

    Discuss cancer pathogenesis and compare and contrast the hallmarks of cancer and the various signaling pathways and metabolic pathways in cancer progression.

    Discuss the connection between mitochondrial metabolism and cancer.

    Discuss the combination of integrative treatment with conventional treatment for breast, prostate, lung and pancreatic cancer.

    Discuss nutrition assessment tools.

    Discuss the role of nutritional oncology and examine the role of diet in altering gene expression.

    Compare and contrast the effects of various dietary regimens and supplements on dysbiosis and mal-digestion.

    Examine nutrients as biological response modifiers.

    Discuss how cancer energy alters copper metabolism.

  30. Learning Outcomes: At the completion of this course, students will be able to:

    • Discuss the role that a high glycemic index diet plays in increasing the risk of a cancer reoccurrence

    • Examine the literature concerning diets that are high in omega-6-fatty acids suppressing the immune system

    • Discuss that a diet high in omega-6-fatty acids may decrease cancer-fighting lymphocytes

    • Discuss that fat cells produce estrogen independent of the ovaries production of estrogen

    • Understand the role that elevated insulin levels have in cancer development and metastasis

    • Describe the role nitrosamines can play in the causation of cancer

    • Compare and contrast studies that show that large amounts of iron and copper can lead to free radical production and increase the patient's risk of cancer and reoccurrence

    • Identify vegetables and fruits that are good to juice

    • Discuss the importance of avoiding malnutrition in a cancer patient

    • Discuss the importance of adequate hydration in a cancer patient

    • Explain the role diet plays in genomic methylation

  31. Major Topics: Major course topics include:

    Selected Cancer Case Reports

    Functional Approach to Botanical-Nutritional Support of Cancer Challenges

    Dietary Stress

    Diabetes, the Metabolic Syndrome & Cancer

    Metabolic Basis of Cancer

    Carcinogenesis: Assaults to Our Aging Genome

    Integrative Oncology: Concepts & Strategies for Clinical Practice

    Integrative Nutrition Assessment of a Cancer Patient's Metabolic Status

    Nutritional Influences

    Nutritional Oncology

    Copper & Cancer

  32. Textbooks: Paradee, A. & Stein, G., eds.,"The Biology and Treatment of Cancer: Understanding Cancer". John Wiley & Sons, New York, 2009.

    Weinberg, R.A., "The Biology of Cancer". Garland, 2006.

    Shankar, S. & Srivastava, R.K., “Nutrition, Diet and Cancer”. Springer, 2012.

  33. Course Readings, Online Resources, and Other Purchases: Additional and appropriate readings will be identified and posted on Blackboard.
  34. Student Expectations/Requirements and Grading Policy: The course requires the completion of 3 case study research papers 15% each 45% of grade. Comprehensive midterm exam 23% of grade. Comprehensive final exam 23% of grade. 5 webcasts 9% of grade.
  35. Assignments, Exams and Tests: The course requires completion of 4 unit self-assessment quizzes, 3 case studies research papers, a comprehensive midterm exam, a comprehensive final exam and 5 webcasts.
  36. Attendance Policy: Course Attendance at First Class Meeting – Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation – Registration - 4.0101,

    Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (

    In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. It’s the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.

  37. Policy on Make-up Work: For documented student absences, such as for illness, students will be allowed to make up any missing case reports or exams. Students will be required to abide by USF policy on academic integrity as described in course syllabus.
  38. Program This Course Supports: M.S. Medical Sciences - Metabolic & Nutritional Medicine concentration.
  39. Course Concurrence Information: None

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