Graduate Studies Reports Access

Graduate Course Proposal Form Submission Detail - GMS6411
Tracking Number - 3071

Edit function not enabled for this course.

Current Status: Approved by SCNS - 2013-04-22
Campus: Tampa
Submission Type: New
Course Change Information (for course changes only):
Comments: to GC 1/25/13; for MSMS -MSM conc - Elective. GC approved 1/28/13. to SYS 1/28/13. to SCNS 2/4/13. Approved eff 4/1/13

Detail Information

  1. Date & Time Submitted: 2013-01-14
  2. Department: Deans Office
  3. College: MD
  4. Budget Account Number: 6108-000
  5. Contact Person: Michael J. Barber, D.Phil.
  6. Phone: 8139749908
  7. Email:
  8. Prefix: GMS
  9. Number: 6411
  10. Full Title: Metabolic Cardiology
  11. Credit Hours: 3
  12. Section Type: C - Class Lecture (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: Y
  15. Are the credit hours variable?: N
  16. Is this course repeatable?:
  17. If repeatable, how many times?: 0
  18. Abbreviated Title (30 characters maximum): Metabolic Cardiology
  19. Course Online?: C - Face-to-face (0% online)
  20. Percentage Online: 0
  21. Grading Option: R - Regular
  22. Prerequisites: None
  23. Corequisites: None
  24. Course Description: Examines the interrelationship between metabolic dis-regulation and cardiovascular disease focusing on the interrelationship between diabetes and increased risk for cardiovascular events.

  25. Please briefly explain why it is necessary and/or desirable to add this course: Replacing Selected Topics with Permanent number; already listed in program
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? This course will be a component of the new Graduate Certificate in Metabolic Cardiology and is an elective for the MSMS -MNM concentration. Metabolic Nutritional Medicine represents a new and evolving discipline in the medical sciences that deals with an integrative and functional medicine approach to healthcare and disease prevention The discipline combines evidence based medicine with new approaches to therapeutics and patient wellness. Nutrition and metabolism represent a critical approaches to understanding and controlling obesity The Metabolic Nutritional Medicine concentration currently has 110 registered students and approx 6 registered for the first course offering.
  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times?
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) All the instructors in the course are M.D., D.O. or Ph.D. or equivalent trained faculty.
  29. Objectives: The course has the following objectives:

    Identifying and discussing the range of cardiovascular drug-nutrient interactions

    Describing the properties of dysglycemia and the properties of metabolic pathways connected to energy balance

    Discussing glucose homeostasis

  30. Learning Outcomes: At the completion of this course, participants will be able to:

    •Identify the sources of acute and chronic toxic metal exposure (i.e. Pb, Hg, Cd & As)

    •Recognize the adverse health effects of toxic metals on cardiovascular disease and overall health

    •Distinguish patients with symptoms of toxic metal accumulation

    •Select appropriate tests for diagnosing toxic metal exposure

    •Discuss treatment strategies for reducing toxic metal exposure and accumulation

    •Understand the physiological changes to the arteries that increase plaque formation

    •Understand the role of hyperglycemia in the formation of plaque

    •Understand the metabolic continuum of non-diabetes, pre-diabetes and diabetes

    •Discuss ways to improve glycemic control in diabetes

    •Discuss AGE and RAGE

    •Understand the role of the mitochondria in the pathophysiology of CVD

    •Explain the PIK3 and MAPK pathways

    •Discuss causes of Insulin Resistance

    •Understand how over expression of the MAPK pathway leads to the changes seen in vascular diseases

    •Understand the role of IR in inflammation and oxidation

    •Understand the role of IR in AGE and clotting

    •Discuss clinical approaches to decrease the implications of insulin resistance

    •Discuss metabolic syndrome and its causes

    •Describe how to identify patients before they exhibit the full syndrome

    •Discuss prevention and treatment

    •Understand how a breakdown in glucose homeostasis causes Metabolic syndrome

    •Discuss the difference between T1DM and Type2DM

    •Understand how changes in mitochondrial function predispose patients to CVD

    •Understand how increased FFA increase the risk for CVD

    •Discuss how someone who is insulin sensitive at birth develops T2DM

    •Develop strategies for avoiding or treating T2DM

    •Discuss new concepts in periodontal diagnosis

    •Discuss practice advancement and improved patient health through collaborative relationships

    •Identify cardiovascular drug nutrient depletions

    •Recommend appropriate nutrients and the dosing required for genomic changes and nutrient repletion

    •Identify symptoms associated with drug related nutrient depletions

    •Discuss how and why the wheat of 2012 is not the wheat of 1960

    •Discuss wheat gliadin, amylopectin and lectin

    •Discuss why elimination of modern wheat can be a strategy in improved health and weight loss

    •Discuss how grains, such as wheat, corn, rye, millet and others, are recent additions to the diet

    •Discuss how grains are responsible for a collection of metabolic distortions that that leads to coronary artery disease and that grain consumption is a coronary risk factor

  31. Major Topics: Major course topics include:

    Cardiovascular Drug-Nutrient Interactions

    Dysglycemia and Cardiovascular Disease

    Insulin, Insulin Resistance & Cardiovascular Disease

    Metabolic Syndrome & Cardiovascular Disease

    Type 1 & 2 Diabetes & Cardiovascular Disease

    Grains & Wheat

    Chelation Therapy, Heavy Metals & Cardiovascular Disease

  32. Textbooks: The course features five recommended textbooks:

    What Your Doctor May Not Tell You About Heart Disease–Grand Central Press–2012–Houston, M. ISBN: 978-1609412548

    •What Your Doctor May Not Tell You About Hypertension–Grand Central Publishing-2003–Houston, M. ISBN: 978-0446690843

    •Handbook of Hypertension–Blackwell & Wiley–2009- Houston, M. ISBN: 978-1405182508

    •Vascular Biology in Clinical Practice-Hanley & Belfus 2001 -Houston, M. ISBN: 978-1560534884

    •Wheat Belly: Lose the Wheat, Lose the Weight & Find Your Path Back to Health -Rodale Books 2011 -Davis, W. ISBN-13: 978-1609611545

  33. Course Readings, Online Resources, and Other Purchases: Additional and appropriate readings will be identified and posted on Blackboard.
  34. Student Expectations/Requirements and Grading Policy: The course requires the completion of 3 case study research papers 15% each 45% of grade. Comprehensive midterm exam 23% of grade. Comprehensive final exam 23% of grade. 5 webcasts 9% of grade.
  35. Assignments, Exams and Tests: The course requires completion of 4 unit self-assessment quizzes, 3 case studies research papers, a comprehensive midterm exam, a comprehensive final exam and 5 webcasts.
  36. Attendance Policy: Course Attendance at First Class Meeting – Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation – Registration - 4.0101,

    Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (

    In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. It’s the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.

  37. Policy on Make-up Work: For documented student absences, such as for illness, students will be allowed to make up any missing case reports or exams. Students will be required to abide by USF policy on academic integrity as described in course syllabus.
  38. Program This Course Supports: M.S in Medical Sciences- Metabolic & Nutritional Medicine concentration.
  39. Course Concurrence Information: None

- if you have questions about any of these fields, please contact or