Graduate Studies Reports Access

Graduate Course Proposal Form Submission Detail - PCB6526
Tracking Number - 3061

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Current Status: Approved by SCNS - 2013-07-01
Campus: Tampa
Submission Type: New
Course Change Information (for course changes only):
Comments: to GC Chair 2/5/13 - fro Cancer Bio PhD Change. Revise Obj. Removed 2nd sentence; need more than 1 obj. emailed faculty 2/7/13. updated; GC apprvd 3/4/13. to USF Sys 3/5/13. to SCNS 4/22/13. Apprd Eff 6/1/13. Nmbr 6521 apprds as 6526

Detail Information

  1. Date & Time Submitted: 2013-01-03
  2. Department: Biology
  3. College: AS
  4. Budget Account Number: 121000
  5. Contact Person: Kenneth L. Wright
  6. Phone: 8137453918
  7. Email:
  8. Prefix: PCB
  9. Number: 6526
  10. Full Title: Cancer Biology IV - Concepts and Techniques in Cancer Genetics
  11. Credit Hours: 3
  12. Section Type: C - Class Lecture (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: Y
  15. Are the credit hours variable?: N
  16. Is this course repeatable?: Y
  17. If repeatable, how many times?: 1
  18. Abbreviated Title (30 characters maximum): Cancer Genetics
  19. Course Online?: C - Face-to-face (0% online)
  20. Percentage Online: 0
  21. Grading Option: -
  22. Prerequisites: none
  23. Corequisites: none
  24. Course Description: This course will explore major concepts in Cancer Genetics, how they are

    derived from experimental results and how they can be applied to

    outstanding problems in Cancer Biology.

  25. Please briefly explain why it is necessary and/or desirable to add this course: Needed to compete with national trends
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? All Cancer Biology PhD students are required to complete this course. The

    course provides a necessary foundation in the principles of genetics as

    it relates to oncology mechanisms.

  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times? Yes, 3 or more times
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) Experience in genetics or cancer biology and a Ph.D. degree are required.
  29. Objectives: The objectives of this course are to first provide a in-depth understanding of molecular and population genetics as they relate to cancer. The second objective is to provide a foundation for understanding how different genetic approaches were instrumental in challenging existing paradigms. The third objective is to provide knowledge on the modern practical uses of genetics to study cancer.
  30. Learning Outcomes: Students will understand the historical and modern approaches to investigate

    genetics changes in cancer. Students will gain knowledge of the

    practical uses of genetics to characterize modern issues in cancer


  31. Major Topics: Two hit Hypothesis; Candidate gene approach; Positional Cloning;

    Microsatellite instability; Chromosomal instability; Modifier genes;

    Model systems in cancer genetics; Haploinsufficiency; Representation

    Difference Analysis; Gene amplification; Structural variation; Cancer

    Epigenetics; SNP analysis.

  32. Textbooks: Required Text: Introduction to Genetic Analysis, 8th Edition, Griffiths,

    Wessler, Lewontin, Gelbart, Suzuki and Miller (2005). Optional

    supplementary text: The Biology of Cancer, Robert Weinberg (2006)

  33. Course Readings, Online Resources, and Other Purchases: Additional reading material will be provided by instructor.
  34. Student Expectations/Requirements and Grading Policy: There will be two exams, each worth 50% of the final grade. The exams will

    be short answer/essay style with an emphasis on the ability to

    synthesize, and apply information in a new context. Final letter grades

    will be assigned with the following scale: A+: 99-100

    points, A: 94-98 points, A-: 90-93 points, B+: 87-89 points, B: 84-86

    points, B-: 80-83 points, C+: 77-79 points, C: 74-76 points, C-: 70-73

    points, D+: 67-69 points, D+: 64-66 points, D-: 60-63 points, F below 60


  35. Assignments, Exams and Tests: Two exams and reading assignments provided by instructor.
  36. Attendance Policy: Course Attendance at First Class Meeting Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation Registration - 4.0101,

    Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (

    In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. Its the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.

  37. Policy on Make-up Work: A missed exam can be made with prior course instructor approval. Students

    will adhere to the University policy to maintain high academic

    integrity. The policy is available at

  38. Program This Course Supports: Cancer Biology
  39. Course Concurrence Information: Biology - Cellular, Molecular, and Microbiology

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