Graduate Course Proposal Form Submission Detail - PCB6526
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Approved by SCNS
Submission Type: New
Course Change Information (for course changes only):
Comments: to GC Chair 2/5/13 - fro Cancer Bio PhD Change. Revise Obj. Removed 2nd sentence; need more than 1 obj. emailed faculty 2/7/13. updated; GC apprvd 3/4/13. to USF Sys 3/5/13. to SCNS 4/22/13. Apprd Eff 6/1/13. Nmbr 6521 apprds as 6526
- Department and Contact Information
Tracking Number Date & Time Submitted 3061 2013-01-03 Department College Budget Account Number Biology AS 121000 Contact Person Phone Kenneth L. Wright 8137453918 email@example.com
- Course Information
Prefix Number Full Title PCB 6526 Cancer Biology IV - Concepts and Techniques in Cancer Genetics Is the course title variable? N Is a permit required for registration? Y Are the credit hours variable? N Is this course repeatable? Y If repeatable, how many times? 1 Credit Hours Section Type Grading Option 3 C - Class Lecture (Primarily) - Abbreviated Title (30 characters maximum) Cancer Genetics Course Online? Percentage Online C - Face-to-face (0% online) 0
This course will explore major concepts in Cancer Genetics, how they are
derived from experimental results and how they can be applied to
outstanding problems in Cancer Biology.
A. Please briefly explain why it is necessary and/or desirable to add this course.
Needed to compete with national trends
B. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service?
All Cancer Biology PhD students are required to complete this course. The
course provides a necessary foundation in the principles of genetics as
it relates to oncology mechanisms.
C. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times?
Yes, 3 or more times
D. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.)
Experience in genetics or cancer biology and a Ph.D. degree are required.
- Other Course Information
The objectives of this course are to first provide a in-depth understanding of molecular and population genetics as they relate to cancer. The second objective is to provide a foundation for understanding how different genetic approaches were instrumental in challenging existing paradigms. The third objective is to provide knowledge on the modern practical uses of genetics to study cancer.
B. Learning Outcomes
Students will understand the historical and modern approaches to investigate
genetics changes in cancer. Students will gain knowledge of the
practical uses of genetics to characterize modern issues in cancer
C. Major Topics
Two hit Hypothesis; Candidate gene approach; Positional Cloning;
Microsatellite instability; Chromosomal instability; Modifier genes;
Model systems in cancer genetics; Haploinsufficiency; Representation
Difference Analysis; Gene amplification; Structural variation; Cancer
Epigenetics; SNP analysis.
Required Text: Introduction to Genetic Analysis, 8th Edition, Griffiths,
Wessler, Lewontin, Gelbart, Suzuki and Miller (2005). Optional
supplementary text: The Biology of Cancer, Robert Weinberg (2006)
E. Course Readings, Online Resources, and Other Purchases
Additional reading material will be provided by instructor.
F. Student Expectations/Requirements and Grading Policy
There will be two exams, each worth 50% of the final grade. The exams will
be short answer/essay style with an emphasis on the ability to
synthesize, and apply information in a new context. Final letter grades
will be assigned with the following scale: A+: 99-100
points, A: 94-98 points, A-: 90-93 points, B+: 87-89 points, B: 84-86
points, B-: 80-83 points, C+: 77-79 points, C: 74-76 points, C-: 70-73
points, D+: 67-69 points, D+: 64-66 points, D-: 60-63 points, F below 60
G. Assignments, Exams and Tests
Two exams and reading assignments provided by instructor.
H. Attendance Policy
Course Attendance at First Class Meeting – Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation – Registration - 4.0101,
Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (http://usfweb2.usf.edu/usfgc/gc_pp/acadaf/gc10-045.htm)
In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. It’s the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.
I. Policy on Make-up Work
A missed exam can be made with prior course instructor approval. Students
will adhere to the University policy to maintain high academic
integrity. The policy is available at
J. Program This Course Supports
- Course Concurrence Information
Biology - Cellular, Molecular, and Microbiology