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Graduate Course Proposal Form Submission Detail - PCB6205

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Current Status: Approved by SCNS - 2013-07-01
Campus: Tampa
Submission Type: New
Course Change Information (for course changes only):
Comments: to GC Chair 2/5/13 - fro Cancer Bio PhD Change; Approved by GC. to USF Sys 2/20/13. to SCNS 2/28/13. Apprd eff 5/1/13

  1. Department and Contact Information

    Tracking Number Date & Time Submitted
    3060 2013-01-03
    Department College Budget Account Number
    Biology AS 121000
    Contact Person Phone Email
    Kenneth L. Wright 8137453918

  2. Course Information

    Prefix Number Full Title
    PCB 6205 Cancer Biology III - Cancer Genomics and Drug Discovery

    Is the course title variable? N
    Is a permit required for registration? Y
    Are the credit hours variable? N
    Is this course repeatable? Y
    If repeatable, how many times? 1

    Credit Hours Section Type Grading Option
    3 C - Class Lecture (Primarily) -
    Abbreviated Title (30 characters maximum)
    Cancer Genomics and Drug Disc.
    Course Online? Percentage Online
    C - Face-to-face (0% online) 0





    Course Description

    An exploration of the normal and abnormal cancer biological processes as

    they pertain to regulation of the genome and of novel cancer gene

    discovery approaches, as well as methodological and conceptual

    approaches to oncologic drug design and devel

  3. Justification

    A. Please briefly explain why it is necessary and/or desirable to add this course.

    Needed to compete with national trends

    B. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service?

    All Cancer Biology PhD students are required to complete this course. The

    course provides a necessary foundation in the principles of basic

    oncology genomics and drug discovery.

    C. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times?


    D. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.)

    Experience in cancer research and a Ph.D. degree are required.

  4. Other Course Information

    A. Objectives

    The primary objective of this course is to provide an in-depth

    understanding of normal and abnormal cell biological processes as they

    relate to genomic regulation. In addition students will gain

    understanding of the principles of cancer gene discovery,

    chemotherapeutic drug action, and rational drug design as they relate to

    cancer biology.

    B. Learning Outcomes

    Students will understand normal and abnormal cellular processes and acquire

    fundamental knowledge of mechanisms of gene regulation and genomic

    control. Students will also understand the underlying principals of

    anti-cancer drug action and discovery.

    C. Major Topics

    Topics to be covered include transcriptional and chromatin control, microRNA

    regulation, DNA replication and damage, mitotic regulation, cancer gene

    discovery, mode of action of chemotherapeutic drugs, and rational drug


    D. Textbooks

    The Biology of Cancer, 1st Edition. (Weinberg) Garland

    Science.; Molecular Cell Biology 7th Edition. (Lodish, Berk, Kaiser,

    Krieger, Bretscher, Ploegh, Amon, Scott) W.H. Freeman & Co.; The

    Molecular Basis of Cancer, 2nd Edition. (Mendelsohn, Howley, Israel and

    Liotta) W.B. Saunders.

    E. Course Readings, Online Resources, and Other Purchases

    Individual lecturers will provide recent primary research articles, and students

    will be expected to participate in the analysis of these papers as part

    of their grade.

    F. Student Expectations/Requirements and Grading Policy

    There are three exams and no final exam. Exams will be of an essay format,

    and questions will be derived from the information covered in the

    lectures and further discussed in the assigned papers. Grades of the

    three exams will each count for 25% of the final grade. Participation in

    the analysis of assigned research papers will count for 20% of the

    final grade. Class attendance will count for the remaining 5% of the

    final grade. Grades will be based on the following scale: A+: 99-100

    points, A: 94-98 points, A-: 90-93 points, B+: 87-89 points, B: 84-86

    points, B-: 80-83 points, C+: 77-79 points, C: 74-76 points, C-: 70-73

    points, D+: 67-69 points, D+: 64-66 points, D-: 60-63 points, F below 60


    G. Assignments, Exams and Tests

    Three exams and additional reading assignments.

    H. Attendance Policy

    Course Attendance at First Class Meeting Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation Registration - 4.0101,

    Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (

    In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. Its the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.

    I. Policy on Make-up Work

    A missed exam can be made with prior course instructor approval. Students

    will adhere to the University policy to maintain high academic

    integrity. The policy is available at

    J. Program This Course Supports

    Cancer Biology

  5. Course Concurrence Information

    Biology - Cellular, Molecular, and Microbiology

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