Graduate Course Proposal Form Submission Detail - PCB6205
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Approved by SCNS
Submission Type: New
Course Change Information (for course changes only):
Comments: to GC Chair 2/5/13 - fro Cancer Bio PhD Change; Approved by GC. to USF Sys 2/20/13. to SCNS 2/28/13. Apprd eff 5/1/13
- Department and Contact Information
Tracking Number Date & Time Submitted 3060 2013-01-03 Department College Budget Account Number Biology AS 121000 Contact Person Phone Kenneth L. Wright 8137453918 firstname.lastname@example.org
- Course Information
Prefix Number Full Title PCB 6205 Cancer Biology III - Cancer Genomics and Drug Discovery Is the course title variable? N Is a permit required for registration? Y Are the credit hours variable? N Is this course repeatable? Y If repeatable, how many times? 1 Credit Hours Section Type Grading Option 3 C - Class Lecture (Primarily) - Abbreviated Title (30 characters maximum) Cancer Genomics and Drug Disc. Course Online? Percentage Online C - Face-to-face (0% online) 0
An exploration of the normal and abnormal cancer biological processes as
they pertain to regulation of the genome and of novel cancer gene
discovery approaches, as well as methodological and conceptual
approaches to oncologic drug design and devel
A. Please briefly explain why it is necessary and/or desirable to add this course.
Needed to compete with national trends
B. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service?
All Cancer Biology PhD students are required to complete this course. The
course provides a necessary foundation in the principles of basic
oncology genomics and drug discovery.
C. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times?
D. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.)
Experience in cancer research and a Ph.D. degree are required.
- Other Course Information
The primary objective of this course is to provide an in-depth
understanding of normal and abnormal cell biological processes as they
relate to genomic regulation. In addition students will gain
understanding of the principles of cancer gene discovery,
chemotherapeutic drug action, and rational drug design as they relate to
B. Learning Outcomes
Students will understand normal and abnormal cellular processes and acquire
fundamental knowledge of mechanisms of gene regulation and genomic
control. Students will also understand the underlying principals of
anti-cancer drug action and discovery.
C. Major Topics
Topics to be covered include transcriptional and chromatin control, microRNA
regulation, DNA replication and damage, mitotic regulation, cancer gene
discovery, mode of action of chemotherapeutic drugs, and rational drug
The Biology of Cancer, 1st Edition. (Weinberg) Garland
Science.; Molecular Cell Biology 7th Edition. (Lodish, Berk, Kaiser,
Krieger, Bretscher, Ploegh, Amon, Scott) W.H. Freeman & Co.; The
Molecular Basis of Cancer, 2nd Edition. (Mendelsohn, Howley, Israel and
Liotta) W.B. Saunders.
E. Course Readings, Online Resources, and Other Purchases
Individual lecturers will provide recent primary research articles, and students
will be expected to participate in the analysis of these papers as part
of their grade.
F. Student Expectations/Requirements and Grading Policy
There are three exams and no final exam. Exams will be of an essay format,
and questions will be derived from the information covered in the
lectures and further discussed in the assigned papers. Grades of the
three exams will each count for 25% of the final grade. Participation in
the analysis of assigned research papers will count for 20% of the
final grade. Class attendance will count for the remaining 5% of the
final grade. Grades will be based on the following scale: A+: 99-100
points, A: 94-98 points, A-: 90-93 points, B+: 87-89 points, B: 84-86
points, B-: 80-83 points, C+: 77-79 points, C: 74-76 points, C-: 70-73
points, D+: 67-69 points, D+: 64-66 points, D-: 60-63 points, F below 60
G. Assignments, Exams and Tests
Three exams and additional reading assignments.
H. Attendance Policy
Course Attendance at First Class Meeting – Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation – Registration - 4.0101,
Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (http://usfweb2.usf.edu/usfgc/gc_pp/acadaf/gc10-045.htm)
In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. It’s the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.
I. Policy on Make-up Work
A missed exam can be made with prior course instructor approval. Students
will adhere to the University policy to maintain high academic
integrity. The policy is available at
J. Program This Course Supports
- Course Concurrence Information
Biology - Cellular, Molecular, and Microbiology