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Graduate Course Proposal Form Submission Detail - GMS6480
Tracking Number - 3041

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Current Status: Approved by SCNS - 2013-07-01
Campus: Tampa
Submission Type: New
Course Change Information (for course changes only): NA
Comments: to GC for 1/14/13. The objectives need verbs. Suggestion to switch the objectives and learning outcomes . Faculty emailed 1/25/13. Updated 1/29/13; reupdated 2/1. Apprd 2/5/13. to USF Sys 2/20/13. to SCNS 2/28/13. Apprd eff 5/1/13. Nmr 6408 app 6480

Detail Information

  1. Date & Time Submitted: 2012-12-04
  2. Department: Deans Office
  3. College: MD
  4. Budget Account Number: 6108-000
  5. Contact Person: Michael J. Barber, D.Phil.
  6. Phone: 8139749908
  7. Email:
  8. Prefix: GMS
  9. Number: 6480
  10. Full Title: Cardiovascular Disease
  11. Credit Hours: 3
  12. Section Type: C - Class Lecture (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: Y
  15. Are the credit hours variable?: N
  16. Is this course repeatable?:
  17. If repeatable, how many times?: 0
  18. Abbreviated Title (30 characters maximum): Cardiovascular Disease
  19. Course Online?: C - Face-to-face (0% online)
  20. Percentage Online: 0
  21. Grading Option: -
  22. Prerequisites: None
  23. Corequisites: None
  24. Course Description: Provide a detailed understanding of the important physiological, nutritional and genetic aspects that influence the progression of cardiovascular disease coupled with an examination of novel therapeutic regimes.

  25. Please briefly explain why it is necessary and/or desirable to add this course: Replacing Selected Topics with Permanent number; already listed in program
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? Metabolic Nutritional Medicine represents a new and evolving discipline in the medical sciences that deals with an integrative and functional medicine approach to healthcare and disease prevention The discipline combines evidence based medicine with new approaches to therapeutics and patient wellness. Nutrition and metabolism represent a critical approaches to understanding and controlling obesity The Metabolic Nutritional Medicine concentration currently has 110 registered students and approx 21 registered for the first course offering.
  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times? Yes, 1 time
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) All the instructors in the course are M.D., D.O. or Ph.D. or equivalent trained faculty.
  29. Objectives: The course objectives include:

    Identify the proximal causes of the cardiovascular disease epidemics in the U.S. and examine the various risk factors for the disease.

    Identify and define the important aspects of maintaining the integrity of cardiovascular function for optimal health.

    Review the principles of cell biology relevant to the cardiovacular system.

    Discribe the critical features of the various forms of cardiovascular disease and their diagnosis.

    Compare and contrast the various methods of invasive and non-invasive cardiovascular testing and their use in diagnosis.

    Identify and examine the various aspects of genetics and epigenetics that are relevant to cardiovascular disease.

    Compare and contrast new and developing therapies to effectively treat the various forms of cardiovascular disease.

    Examine the application of nutritional and dietary therapies for prevention and treatment of cardiovascular disease.

    Explore the use of illustrative patient cases to provide detailed insights into the diagnosis and management of cardiovascular disease.

  30. Learning Outcomes: At the completion of this course, participants will be able to:

    •Discuss the pathophysiology, clinical presentation, prevention, and treatment of immunologic vascular disease.

    •Discuss, review and describe invasive and non-invasive cardiovascular testing methodologies.

    •Discuss the role of nutrition in cardiovascular disease and provide appropriate nutrition suggestions.

    •Define and discuss the role of nutrigenomics, proteomics and genetic SNPs in cardiovascular disease.

    Examine examples of SNPs specific for cardiovascular disease.

    •Describe the role of stress, anxiety, depression, and sleep in the prevention and treatment of cardiovascular disease.

    •Explain the importance of optimal sex hormonal balance and function in cardiovascular protection in both men and women and compare and contrast the differences between the sexes.

    Discribe the metabolic roles of thyroid hormones.

    •Compare and contrast the protective and treatment roles that optimal thyroid function plays in cardiovascular health.

    •Discuss the role of nutrition and dietary patterns in a lifestyle approach for prevention and treatment of cardiovascular disease.

    •Discuss how specific macronutrients, micronutrients, and phytonutrients impact prevention and treatment of cardiovascular disease.

    •Describe the scientific rationale and mechanisms for the clinical application of nutritional therapies in cardiovascular disease.

  31. Major Topics: Major course topics include:

    Hormones & the Cardiovascular System.

    The Role of Stress, Anxiety, Depression, Emotions & Sleep in Cardiovascular Disease.

    Nutrition & Cardiovascular Disease.

    Invasive & Selective Non-Invasive Cardiovascular Testing.

    Immunologic Mechanisms in Cardiovascular Disease.

    Nutrigenomics, Proteomics & Metabolomics in Cardiovascular Disease.

    Cardiovascular Genetics, Epigenetics & Single Nucleotide Polymorphisms.

  32. Textbooks: •What Your Doctor May Not Tell You About Heart Disease – Grand Central Press – 2012 – Houston, M. –ISBN: 978-1609412548

    •What Your Doctor May Not Tell You About Hypertension – Grand Central Publishing - 2003 – Houston, M. - ISBN: 978-0446690843

    •Handbook of Hypertension – Blackwell and Wiley – 2009 - Houston, M. - ISBN: 978-1405182508

    •Vascular Biology in Clinical Practice - Hanley & Belfus - 2001 - Houston, M. - ISBN: 978-1560534884

  33. Course Readings, Online Resources, and Other Purchases: Additional and appropriate readings will be identified and posted on Blackboard.
  34. Student Expectations/Requirements and Grading Policy: The course requires the completion of 3 case study research papers 15% each 45% of grade. Comprehensive midterm exam 23% of grade. Comprehensive final exam 23% of grade. 5 webcasts 9% of grade.
  35. Assignments, Exams and Tests: The course requires completion of 4 unit self-assessment quizzes, 3 case studies research papers, a comprehensive midterm exam, a comprehensive final exam and 5 webcasts.
  36. Attendance Policy: Course Attendance at First Class Meeting – Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation – Registration - 4.0101,

    Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (

    In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. It’s the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.

  37. Policy on Make-up Work: For documented student absences, such as for illness, students will be allowed to make up any missing case reports or exams Students will be required to abide by USF policy on academic integrity as described in course syllabus.
  38. Program This Course Supports: M.S in Medical Sciences- Metabolic & Nutritional Medicine concentration
  39. Course Concurrence Information: None

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