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Graduate Course Proposal Form Submission Detail - PAS6023
Tracking Number - 3015

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Current Status: Approved by SCNS - 2013-07-01
Campus: Tampa
Submission Type: New
Course Change Information (for course changes only):
Comments: to GC 1/14/13. for MA in P.A.; Needs Objectives revised; missing text info. Faculty lemailed 1/25/13. Updated 1/28/13. Approved. to USF Sys 2/20/13. to SCNS 2/28/13. Apprd Eff 4/1/13.

Detail Information

  1. Date & Time Submitted: 2012-11-26
  2. Department: Graduate School
  3. College: MD
  4. Budget Account Number: HSC-10009-611600-000000-0000000
  5. Contact Person: Larry Collins
  6. Phone: 813-396-9424
  7. Email:
  8. Prefix: PAS
  9. Number: 6023
  10. Full Title: Pharmacotherapeutics I
  11. Credit Hours: 4
  12. Section Type: C - Class Lecture (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: N
  15. Are the credit hours variable?: N
  16. Is this course repeatable?:
  17. If repeatable, how many times?: 0
  18. Abbreviated Title (30 characters maximum): PHARMACOTHERAPEUTICS
  19. Course Online?: C - Face-to-face (0% online)
  20. Percentage Online: 100
  21. Grading Option: -
  22. Prerequisites: N/A
  23. Corequisites: N/A
  24. Course Description: The first semester of a two-semester overview of pharmacology. The course will focus on the principles of pharmacologic action, and the therapeutic indications for pharmaceutical preparations used in clinical medicine.

  25. Please briefly explain why it is necessary and/or desirable to add this course: Needed for new program/concentration/certificate
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? Consistent with other Physician Assistant Degree Programs
  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times? No
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) PA, MD, PhD, ARNP, MSW
  29. Objectives: Upon completion of this course the first-year physician assistant student will be able to:

    1. Identify and apply basic principles of pharmacology, including: pharmacokinetics, pharmacodynamics, receptors, dose-response, and drug interactions as it relates to the selection of medications for medical diseases and conditions.

    2. Identify the major classes of drugs and the specific drugs within them and their therapeutic uses in the treatment of the following organ systems covered in Pathophysiological Basis of Disease I: cardiovascular, ophthalmology and otorhinolaryngology (EENT), pulmonary, infectious disease, renal, dermatology, neurological/psychiatric.

    3. Identify and apply the basic properties, routes of administration, relative half-lives, target organ (or system), and mechanisms of action of commonly used drugs from each of the organ systems covered in Pathophysiological Basis of Disease II: cardiovascular, ophthalmology and otorhinolaryngology (EENT), pulmonary, infectious disease, renal, dermatology, neurological, and psychiatric.

    4. Apply the principles of clinical pharmacotherapeutics for the classes of drugs covered in this course, to include the appropriate choice of drugs, therapeutic uses, their safe dose schedule and route of administration, adverse drug interactions, side effects, and cost-effectiveness.

    5. Describe principles of safe administration of medications.

    6. Demonstrate clinical reasoning and an evidence based approach to the selection choice of commonly used medications for the organ system disease states covered in the course.

    7. Contrast the principles of pharmacotherapeutics across the lifespan including the effects of race, gender and, ethnicity.

    8. Investigate technologies and systems used for medication administration.

    9. Discuss legal and ethical parameters of medication administration.

  30. Learning Outcomes: Upon completion of Pharmacotherapeutics I the student should exhibit the following knowledge, skills, and behaviors:


    1. Demonstrate knowledge concerning each major drug class discussed in the course, including:

    a. prototype drug(s),

    b. mechanism(s) of action,

    c. important therapeutic actions and applications, and

    d. important (prevalent or life-threatening) adverse effects;

    2. Demonstrate knowledge of the variations in drug response between individual patients, based upon disease, genetic traits, or other innate characteristics;

    3. Demonstrate knowledge of the effect of age on pharmacodynamics, pharmacokinetics, and responses to therapy, with an emphasis on geriatric patients;

    4. Develop an adequate basis of knowledge in pharmacology on which to build as the student advances through the clinical clerkship rotations;

    5. Develop knowledge of drug classes and mechanisms into which additional drugs can be incorporated, compared, and contrasted as new drugs are developed and as the practice of medicine dictates.


    1. Demonstrate an understanding of the general types and clinical usage of drugs for treating diseases of each organ system;

    2. Demonstrate the ability to recognize and understand the physicochemical and physiological factors that affect the absorption, distribution, metabolism, and elimination of drugs, and how these relate to pharmacokinetics;

    3. Demonstrate the ability to interpret dose-response relationships for both desired and undesired drug effects;

    4. Demonstrate an understanding of drug-receptor interactions and allied molecular phenomena at a basic level;

    5. Demonstrate ability to interpret and analyze literature related to drugs.

    Attitudes and behaviors:

    1. Demonstrate professional behavior during activities in the course by being in attendance when required, on time, attentive, and a considerate and active participant in discussions.

  31. Major Topics: Pharm I Topics:


    Prescription Writing



    Antivirals (non-HIV drugs)

    GI Drugs



    Hormonal contraceptives

    Osteoporosis and Menopause Medications

  32. Textbooks: TEXT: Pharmacology. (3rd Ed). Brenner GM, Stevens CW. Philadelphia, PA: Saunders/Elsevier; 2010.

    Current Medical Diagnosis & Treatment 2012. (51st Ed). McPhee SJ, Papadakis MA. New York, NY: McGraw-Hill; 2012.

    Physician Assistant: A Guide to Clinical Practice. (4th Ed) Ballweg R, Stolberg S, Sullivan E. Philadelphia, PA: Saunders/Elsevier; 2008.

    ‘Epocrates’ software for Smartphone or laptop

  33. Course Readings, Online Resources, and Other Purchases:
  34. Student Expectations/Requirements and Grading Policy: Expectations of Students

    You are part of a community of learners that includes students, faculty and support personnel. As part of that community, we all have the responsibility to actively contribute to the educational process. Your responsibilities include:

    • Attendance

    o As a professional in the field, you should make a conscientious effort to attend each session and to be on time. History and experience show that students who attend classes regularly do much better work and earn better grades. Attendance in lectures is strongly encouraged.

    o Student attendance and active participation in small groups will be mandatory. Attendance records will be kept to aid in tracking student participation. Your presence is required for effective team function, and you will be graded on team participation as a measure of your professional competence.

    • Adequate preparation for class

    o This is particularly important in the small group sessions where students are expected to read the article and answer the worksheet questions in advance.

    • Active participation

    o You are expected to take an active role in your own education by participating actively in the small group discussion. Every student has some knowledge and experience to contribute.

    o Being able to make a cogent and thoughtful argument are skills worth developing early in your training as you will be called upon to do this repeatedly in your clinical years and beyond.

    • Independent and group study

    o Another way to enhance your learning is to participate in a study group. You will get as much out of your education as you put into it. The more independent work you do – additional readings, practicing skills – the better prepared you will be. Interacting with your classmates in active discussions of the material is a terrific way to test your assumptions.

    o PLEASE NOTE – If you participate in a study group to prepare, you should not divide the questions among the group, unless specifically instructed to do so by your instructor. It is fine to discuss the questions on the worksheets and the articles, but the answers you bring to small group must be your own.

    • Technology

    o You must be competent in the use of email and the E*Value/Blackboard (Bb) course management system. Information and grades will be disseminated via E*Value/Bb.

    o Assignments will be submitted electronically to the course site. It is your responsibility to understand this technology.

    • Strive for excellence - Do not be satisfied with minimal contributions and performance.

    Test #1 – 26.7%

    Test #2 – 26.7%

    Test #3 – 26.7%

    Prescription Exercises – 10%

    Formulary Assignment – 10%

  35. Assignments, Exams and Tests: I. Testing

    There will be three exams. Each exam will cover 3-4 topic areas. Tests will consist of multiple-choice and matching questions, plus 2-3 prescriptions to be written using a PDA or laptop.

    II. Prescription Exercises

    There will be eight prescription-writing exercises to be done as homework following specific lectures. Grading of these exercises is described below.

    Prescription-writing exercises will count for 10% of the course grade. There are eight prescriptions, and each will be worth 100 points. At the end of the quarter, the scores will be averaged for all eight prescriptions and the average score will be entered in the course grading formula.

    Grading is based on the professional judgment of the course coordinator, and includes neatness, attention to detail, correct drug choice, correct dosing, patient instructions, etc. Points will be subtracted for minor errors in 5 to 10 point increments at the discretion of the faculty member doing the grading. See the grading rubric in the course syllabus for more details.

    If a prescription needs to be re-done, it will be counted as a temporary failure and re-graded at 80% if the revised version is satisfactory. If it is rejected a second time, it will be scored at 50%. Late prescriptions will be penalized and scored no higher than 80%. Prescriptions that are late without permission by more than 2 days will be worth 0%. In order to successfully complete this course requirement, all assignments must be submitted, regardless of the grade.

    III. Formulary Assignment

    Students will be assigned to small groups of 4-6 students. Each group will work on the following scenario:

    “You have accepted a job at a community clinic. The clinic has an in-house pharmacy that dispenses medications for common out-patient conditions. Patients pay for their medications on a sliding scale, which often does not cover the full cost to the clinic of purchasing the drugs. Your job is to advise the pharmacist on which medications to stock for a given condition or drug class. The recommendations should be based on considerations of efficacy, safety, and cost.”

    Each student in the group is responsible for identifying an article from the medical literature supporting their choice of drugs and presenting it to the group. The group is responsible for choosing no more than 6 drugs for the clinic formulary for the assigned condition or drug class. The 6 drugs can include OTC as well as prescription medications. The group will turn in the list of recommended drugs along with a 1-2 page justification for the choices, and copies of the articles used to choose the drug list. The assignment will be graded based on the quality of the articles chosen (e.g., EBM-type articles, expert review panel consensus articles, etc.) and the persuasiveness of the summary justifying the final list of recommended drugs. All members of the group will receive the same grade.

  36. Attendance Policy: Course Attendance at First Class Meeting – Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation – Registration - 4.0101,

    Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (

    In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. It’s the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.

  37. Policy on Make-up Work: Didactic Attendance Policies

    Students are encouraged to attend all scheduled hours of instruction. Mandatory sessions and participation requirements are listed on the final page of this syllabus. Recognizing that situations arise which require students to miss time from course responsibilities, the procedures presented below will be followed when absence is necessary.

    1. Religious Observances

    All students, faculty and staff at the University of South Florida have a right to expect that the University will reasonably accommodate their religious observances, practices and beliefs. Students are expected to attend classes and take examinations as determined by the University. The University will attempt, at the beginning of each academic term, to provide written notice of the class schedule and formal examination periods. The University, through its faculty, will make every attempt to schedule required classes and examinations in view of customarily observed religious holidays of those religious groups or communities comprising the University’s constituency. Any student who believes that he/she has been treated unfairly with regard to the above should contact the Office of Student Affairs.

    2. Lectures

    a. Emergencies for Personal Illness, Family Illness, etc.

    The student must contact both the Course Directors by e-mail or telephone and Student Affairs by e-mail or telephone to report his/her absenteeism on the first day of being absent. He/she should indicate the nature of the emergency or unexpected illness. The student must also complete and submit the Absence Report Form. Specifics on planned and unplanned absences, as well as unexcused absences, are listed below.

    b. Exam Attendance Procedures

    Students are expected to attend all scheduled hours of instruction. However, attendance at all examinations is mandatory, and all students should take the examinations on the day and time scheduled.

    Planned Absence

    Absence for attendance at a professional meeting or other educational or research related activity should be submitted for approval to the Course Directors at least 6 weeks prior to the event. Each request for absence will be considered on a case-by-case basis. Personal travel plans should not be considered valid excuses for missing an exam.

    To receive an excused, planned absence, the student must submit a completed Exam Absence Request form to the Course Directors. A copy of the written request must also be submitted to the Office of Student Affairs as soon as possible before the exam occurs. The Course Directors or designee will make the final determination to grant or deny the request and will inform the Office of Student Affairs of the decision. The Office of Student Affairs will subsequently notify the student and the Office of Educational Affairs.

    Unplanned Absence

    If the student has an unanticipated, unplanned absence on the day of an exam, he/she must contact Student Affairs by 8:30 a.m. on the day of the exam. When the student returns to school he/she must fill out and sign the Absence Report form. Documentation for the absence to be excused (e.g. physician’s note, accident report, etc.) will be at the discretion of the OSA.

    Students who miss an examination for any reason are required to contact the Office of Educational Affairs (974-2435) prior to returning to class to determine the date and time of the make-up examination. Dates and times of make-up examinations are determined by the Program Director in consultation with Course Directors.

    In general, make-up examinations must be taken within 48 hours of the original examination date. If a student’s absence from an examination is unexcused, the grade recorded for the exam will be the student’s actual score or 69, whichever is lower, and will not include a group score. A second unexcused absence will result in a grade of “0” and action taken by the Academic Performance Review Committee (APRC) regarding professionalism.

    3. Mandatory Course-Specific Events

    In addition to examinations, the following are all considered mandatory events:

    a. Laboratories

    b. Small group conferences

    c. Problem-solving sessions

    d. Team Based Learning sessions

    e. Large group/Active Learning sessions

    Planned Absence

    In general, in order to be excused from one of these events, the same procedure for examinations is followed. The student must first directly contact the Course Directors with a copy of the request to Student Affairs. The Absence Request form should be completed and given to the Course Directors as soon as possible for planned absences. The Course Directors will make the determination to grant or deny a request in addition to any required remediation.

    Unplanned Absence

    An unanticipated absence on the day of an event requires notification of the Course Directors and Student Affairs. Upon returning to campus, the Absence Report form should be completed and given to the Course Directors. The Course Directors will make the determination to grant or deny the absence in addition to any required remediation.

    Students who miss course-specific mandatory events are expected to acquire the same level of competency as other students involved in the course. Therefore, students with an excused absence may be assigned work to complete by the Course Directors in order to remediate. In the case of an unexcused absence the Course Directors may assign a “0” or no credit for the missed work and/or require other remediation at their discretion. Multiple absences, or a prolonged absence, could result in failure of the course or a grade of “Incomplete”, at the discretion of the Course Directors. In any event all absences for course-specific mandatory events and the outcome should be reported to the OSA by the Course Directors.

    Sign-in sheets will be used for laboratories, case studies and group discussion conferences to determine attendance (Sign-in sheets WILL NOT be used for lectures). Signing an attendance roster when you didn’t attend or arrive late to a lab, or signing the roster for another student is considered an unprofessional act and a violation of the honor code.

  38. Program This Course Supports: Physician Assistant
  39. Course Concurrence Information: n/a

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