Graduate Course Proposal Form Submission Detail - GMS6010
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Approved by SCNS
Submission Type: New
Course Change Information (for course changes only):
Comments: to GC 8/29/12. Elective for MSMS program. Appd by GC Chair. To USF Syst 8/31/12. to SCNS 9/14/12. Eff 11/2/12
- Department and Contact Information
Tracking Number Date & Time Submitted 2886 2012-06-18 Department College Budget Account Number Deans Office MD 6108-000 Contact Person Phone Michael J. Barber, D.Phil. 8139749908 firstname.lastname@example.org
- Course Information
Prefix Number Full Title GMS 6010 Personalized Medicine Is the course title variable? N Is a permit required for registration? Y Are the credit hours variable? N Is this course repeatable? If repeatable, how many times? 0 Credit Hours Section Type Grading Option 3 C - Class Lecture (Primarily) R - Regular Abbreviated Title (30 characters maximum) Personalized Medicine Course Online? Percentage Online C - Face-to-face (0% online) 0
The course is designed to introduce the various principles that influence the discipline of genomics and the application to personalized medicine which utilizes information on genes, proteins and the environment to prevent, diagnose and treat disease.
A. Please briefly explain why it is necessary and/or desirable to add this course.
Replacing Selected Topics with Permanent number; already listed in program
B. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service?
Metabolic Nutritional Medicine represents a new and evolving discipline in the medical sciences that deals with an integrative and functional medicine approach to healthcare and disease prevention The discipline combines evidence based medicine with new approaches to therapeutics and patient wellness. Personalized medicine represents a critical approache to understanding and controlling diseases such as cardiovascular disease, diabetes, cancer and obesity. The Metabolic Nutritional Medicine concentration currently has 106 registered students and approx 30 registered for the first course offering.
C. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times?
D. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.)
All the instructors in the course are M.D., D.O. or Ph.D. or equivalent trained faculty.
- Other Course Information
The course has the following objectives:
Comparing and contrasting the various definitions of personalized medicine
Examining the data from the human genome project and the application to medicine
Describing the linkage between genomics and personalized medicine
Reviewing the structure and function of chromosomes and genes and their products
Discussing genetic and environmental interactions in the etilogy of human disease
Comparing and contrasting molecular diagnostic techniques
Identifying and discussing the use of biomarkers for disease diagnostics
Reviewing the principles of pharmacogenomics and the application to drug metabolism
Discussing personalized medicine informatics
Examining the application of personalized medicine to selected diseases such as cancer, neurodegeneration, cardiovascular disease, allergy and immunology.
Examining the role of nutrition in personalized medicine
Discussing regulatory and ethicals aspects of personalized medicine
B. Learning Outcomes
At the completion of this course, participants will be able to:
•Discuss the ability to predict an individual’s susceptibility to disease, based upon genetic, genomic and other factors
•Compare and contrast the properties of useful diagnostic tools and individualized programs designed to enhance disease prevention, based on knowledge of an individual’s susceptibility
•Discuss the detection of the onset of disease earlier and before it is clinically evident, based on newly discovered biological markers that arise from changes at the molecular level
•Develop new therapeutic modalities designed to preempt disease progression, as a result of early detection
•Target medicines and their doses more precisely and safely to each patient, on the basis of a deep understanding of disease mechanism and the role that genetic and genomic factors play in the individual response to drugs
•Discuss the application of the principles of personalized medicine to specific diseases such as cancer, cardiovascular and infectious disease.
C. Major Topics
Course topics include:
Introduction to Personalized Medicine
Molecular Biology of Personalized Medicine
The Role of Molecular Diagnostics in Personalized Medicine
Pharmacogenetics and Pharmacogenomics
Personalized Medicine Informatics
Personalized Medicine and Cardiovascular Disease
Personalized Medicine in Allergy, Immunology and Infectious Disease
The Role of Nutrition in Personalized Medicine
Regulatory and Ethical Aspects of Personalized Medicine
Business Principals and Personalized Medicine
Future Advances in Personalized Medicine
The course features a single textbooks that provides expert coverage of the course material:
Jain, K.K., “Textbook of Personalized Medicine”. Springer, 2009.
E. Course Readings, Online Resources, and Other Purchases
Additional and appropriate readings will be identified and posted on Blackboard.
F. Student Expectations/Requirements and Grading Policy
The course requires the completion of 3 case studies research papers 15% each 45% of grade. Comprehensive midterm exam 23% of grade. Comprehensive final exam 23% of grade. Discussion topics 9%.
G. Assignments, Exams and Tests
The course requires completion of 4 unit self-assessment quizzes, 3 case studies research papers, a comprehensive midterm exam, a comprehensive final exam and course discussion topics.
H. Attendance Policy
Course Attendance at First Class Meeting – Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation – Registration - 4.0101,
Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (http://usfweb2.usf.edu/usfgc/gc_pp/acadaf/gc10-045.htm)
In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. It’s the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.
I. Policy on Make-up Work
For documented student absences such as for illness students will be allowed to make up any missing case reports or exams Students will be required to abide by USF policy on academic integrity as described in course syllabus.
J. Program This Course Supports
M.S in Medical Sciences- Metabolic & Nutritional Medicine concentration
- Course Concurrence Information