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Graduate Course Proposal Form Submission Detail - GMS6458
Tracking Number - 2806

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Current Status: Approved by SCNS - 2012-05-14
Campus: Tampa
Submission Type: New
Course Change Information (for course changes only):
Comments: to GC 4/2/12; to USF Syst 4/5/12; to GC 4/16/12; to SCNS 4/16/12. SCNS appd eff 6/1/12. Number 6456, appd as 6458

Detail Information

  1. Date & Time Submitted: 2012-02-28
  2. Department: Deans Office
  3. College: MD
  4. Budget Account Number: 6108-000
  5. Contact Person: Michael J. Barber, D.Phil.
  6. Phone: 8139749908
  7. Email:
  8. Prefix: GMS
  9. Number: 6458
  10. Full Title: Metabolic Triads
  11. Credit Hours: 3
  12. Section Type: C - Class Lecture (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: Y
  15. Are the credit hours variable?: N
  16. Is this course repeatable?:
  17. If repeatable, how many times?: 0
  18. Abbreviated Title (30 characters maximum): Metabolic Triads
  19. Course Online?: C - Face-to-face (0% online)
  20. Percentage Online: 0
  21. Grading Option: R - Regular
  22. Prerequisites: None
  23. Corequisites: None
  24. Course Description: Detailed understanding of the important aspects of the various organ and metabolic pathway interrelationships together with various disturbances that can result in a wide variety of pathophysiological diseases.

  25. Please briefly explain why it is necessary and/or desirable to add this course: Replacing Selected Topics with Permanent number; already listed in program
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? Metabolic Nutritional Medicine represents a new and evolving discipline in the medical sciences that deals with an integrative and functional medicine approach to healthcare and disease prevention The discipline combines evidence based medicine with new approaches to therapeutics. Metabolic triads represents an integrated critical approach to understanding the structure and function of several organs systems and their interactions.

    The Metabolic Nutritional Medicine concentration currently has 110 registered students and approx 30 registered for the first course offering.

  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times?
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) All the instructors in the course are M.D., Ph.D. or combined doctoral degree faculty.
  29. Objectives: This course has the following objectives:

    Identify the various metabolic triads and the corresponding organ or system components.

    Discuss how the metabolic triads can be used to describe the function of five organ/system groupings.

    Develop a detailed understanding of intermediary metabolism today as one of the most challenging health problems and one with an extraordinary need for early intervention and prevention to slow or halt disease progression.

    Discuss how the various triads and their properties can be integrated into the concept of a "metabolic code".

    Define important physiologic interrelationships that mediate health and disease.

    Discuss how the the Metabolic Triad system creates a framework to assess and treat patients by first understanding the important interrelationship hierarchies, and then provide specific treatment recommendations.

    Discuss a variety of case-based patient examples for all five triads that provide illustrative approaches to diagnosis and therapy.

  30. Learning Outcomes: At the completion of this course, participants will be able to:

    •Describe how the Metabolic Code Triads work

    •Discuss an example of a triad, The Brain-Gut-Inflammation Triad and see how triad organizational thought would be helpful in helping the student organize complex patient therapies

    •Summarize the core principles learned in this course concerning the Metabolic Code Triad System

    •Review normal physiology of adrenals, thyroid, and pancreas

    •Review common ways patients are presented with multiple metabolic abnormalities

    •Discuss natural and hormonal treatment strategies for cortisol, insulin and thyroid

    •Describe the physiologic relationships between the digestive tract, immune system and brain

    •Discuss common clinical presentations within the proposed framework of Gut-Immune-Brain

    •Compare and contrast treatment options and strategies specific for Gut-Immune-Brain pathologies

    •Describe basic physiologic connections between the mind, brain and heart mediated through mechanisms such as Heart Rate Variability, depression, stress, and the immune system

    •Explain common clinical presentations within the cardiopulmonary-neuro-vascular triad

    •Discuss ways to treat complex conditions within this triad framework

    •Explain the physiology of the most important detoxification organs and their pathways to remove toxins

    •Describe the most common toxins, both exogenous and endogenous, which contribute to medical illness

    •Discuss treatment strategies for removal of toxins safely and effectively

    •Examine ways to mitigate toxins in the home environment

    •Discuss the role of sex hormones in the aging male and female

    •Describe common presentations of sex hormone dys-regulation and the associated signs and symptoms

    •Discuss methods of balancing and replacing estrogen, progesterone, and testosterone safely and effectively through the use of natural products and hormone replacement therapy

  31. Major Topics: Major course topics include:

    Introduction to the Triads

    Triad 1 - Adrenals Thyroid Pancreas

    Triad 2 - Gut Immune Brain

    Triad 3 - Cardio-Pulmonary Neuro-Vascular

    Triad 4 - Liver Lymph Kidney

    Triad 5 - Estrogen Progesterone Testosterone

  32. Textbooks: None.
  33. Course Readings, Online Resources, and Other Purchases: Additional and appropriate readings will be identified and posted on Blackboard.
  34. Student Expectations/Requirements and Grading Policy: 3 case studies research papers 15% each 45% of grade Comprehensive midterm exam 23% of grade Comprehensive final exam 23% of grade 5 webcasts 9% of grade.
  35. Assignments, Exams and Tests: The course requires completion of 4 unit quizzes self assessments, 3 case studies research papers, Comprehensive midterm exam, Comprehensive final exam, 5 webcasts.
  36. Attendance Policy: Course Attendance at First Class Meeting – Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation – Registration - 4.0101,

    Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (

    In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. It’s the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.

  37. Policy on Make-up Work: For documented student absences such as for illness students will be allowed to make up any missing case reports or exams Students will be required to abide by USF policy on academic integrity as described in course syllabus.
  38. Program This Course Supports: M.S. in Medical Sciences: Metabolic & Nutritional Medicine concentration
  39. Course Concurrence Information: None

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