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Graduate Course Proposal Form Submission Detail - NGR6152
Tracking Number - 2783

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Current Status: Approved by SCNS - 2012-05-15
Campus: Tampa
Submission Type: New
Course Change Information (for course changes only):
Comments: for MS in Nursing; to GC 4/2/12; to USF Syst for conc 4/5/12; to GC 4/16/12; to SCNS 4/16/12. SCNS Appd eff 6/1/12. Nbr 6141 appd as 6152

Detail Information

  1. Date & Time Submitted: 2012-02-21
  2. Department: Nursing
  3. College: NR
  4. Budget Account Number: 620100020
  5. Contact Person: Dewel Lindsey
  6. Phone: 8133969978
  7. Email:
  8. Prefix: NGR
  9. Number: 6152
  10. Full Title: Advanced Physiology and Pathophysiology
  11. Credit Hours: 4
  12. Section Type: D - Discussion (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: N
  15. Are the credit hours variable?: N
  16. Is this course repeatable?:
  17. If repeatable, how many times?: 0
  18. Abbreviated Title (30 characters maximum): Advan Physio and Patho
  19. Course Online?: B - Face-to-face and online (separate sections)
  20. Percentage Online: 20
  21. Grading Option: R - Regular
  22. Prerequisites:
  23. Corequisites:
  24. Course Description: In-depth review of research findings in foundational sciences of human physiology. Findings will be applied to mechanisms important in disease pathogenesis, pathophysiology, and clinical manifestations in selected disease states throughout the lifespan.

  25. Please briefly explain why it is necessary and/or desirable to add this course: Needed for accreditation
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? Required as part of MS program and NP core.
  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times? No
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) Knowledge of specific content area
  29. Objectives: 1. Describe mechanisms by which the latest immunological, genetic, epigenetic, and molecular biology discoveries influence the pathogenesis of common diseases.

    2. Analyze perturbations in normal physiology that lead to pathophysiological phenomena across the life span.

    3. Discuss the mechanisms by which developmental factors, environment, and psychosocial factors influence physiology and lead to disease states.

    4. Describe the pathogenesis, and clinical manifestations of common altered health state.

    5. Analyze bio-behavioral responses to illness and treatment modalities.

  30. Learning Outcomes: 1. Apply etiology, epidemiology, and pathophysiology of different diseases according to the gender and age to patient data.

    2. Integrate knowledge of physiology and pathophysiology to health promotion and disease prevention.

  31. Major Topics: 1. Human physiological and pathophysiology mechanisms across the life span

    a. Non age specific

    b. Infant

    c. Childhood

    d. Adolescence

    e. Adult

    f. Older Adult

    2. Cell, tissue, organ and organism: Interpreting the science of human physiology

    3. Genetic and epigenetic mechanisms operating from pre-implantation through old age

    4. Transcription factors, pathways and normal cell physiology: Molecular biological regulation of health

    5. Immunological mechanisms that protect health, through identification of self and recognition of non-self

    6. Normal and healthy protections from disease: Inflammation, Apoptosis, Autophagy, Cell Senescence and Renewal

    7. Perturbations in normal physiology that lead to disease: Inflammation, Autoimmunity, Allergy

    8. Perturbations continued: Mutagenesis, Mutational errors, Carcinogenesis

    9. Perturbations continued: Metabolic Imbalance: the gene, environment interaction in diabetes, metabolic syndrome, obesity and cardiovascular disease

    10. Perturbations continued: Neurochemistry, Environment, and genetics interaction in common mental health disorders (depression, anxiety, PTSD, sleep disorders)

    11. Allostasis and chronic disease: Interpreting the interactions of genetics, environment, and behavioral influences in chronic disease progression

    12. Common and unique manifestations of illnesses across the lifespan: Symptoms, and signs, clinical and laboratory data interpretation

    13. The bio-behavioral response to illness: from sickness behavior to anniversary death

    14. The bio-behavioral response to treatment modalities and the future of personalized medicine

  32. Textbooks: McCance, K.L., & Huether, S.E. (2010). Pathophysiology: The biological basis for

    diseases in adults & Children. (6th ed.) St. Louis, MO; Mosby Elsevier.

  33. Course Readings, Online Resources, and Other Purchases:
  34. Student Expectations/Requirements and Grading Policy: Papers

    Class Presentations

    Class Discussion

  35. Assignments, Exams and Tests: Papers

    Class Presentations

  36. Attendance Policy: Course Attendance at First Class Meeting Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation Registration - 4.0101,

    Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (

    In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. Its the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.

  37. Policy on Make-up Work:
  38. Program This Course Supports: Master's Program
  39. Course Concurrence Information: None

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