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Graduate Course Proposal Form Submission Detail - GMS6409
Tracking Number - 2700

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Current Status: Approved by SCNS - 2016-01-01
Campus: Tampa
Submission Type: New
Course Change Information (for course changes only):
Comments: to gc 2/6/12- Approved 2/20/12; to USF Sys 2/27/12; to SCNS 3/6/12; Updated - approval not received; confirmed 11/24/15; submt to SCNS 11/24/15. Approved effective 1/1/16


Detail Information

  1. Date & Time Submitted: 2011-12-20
  2. Department: Deans Office
  3. College: MD
  4. Budget Account Number: 6108
  5. Contact Person: Michael J. Barber, D.Phil.
  6. Phone: 8139749908
  7. Email: mbarber@health.usf.edu
  8. Prefix: GMS
  9. Number: 6409
  10. Full Title: Integrated Cardiovascular Biology
  11. Credit Hours: 3
  12. Section Type: C - Class Lecture (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: Y
  15. Are the credit hours variable?: N
  16. Is this course repeatable?:
  17. If repeatable, how many times?: 0
  18. Abbreviated Title (30 characters maximum): Int Cardiovascular Biology
  19. Course Online?: C - Face-to-face (0% online)
  20. Percentage Online: 0
  21. Grading Option: R - Regular
  22. Prerequisites: None
  23. Corequisites: None
  24. Course Description: Designed to give a broad understanding of the biology of the cardiovascular system and the various pathophysiolgical changes that cause chronic heart disease together with discussion of appropriate therapies.

  25. Please briefly explain why it is necessary and/or desirable to add this course: Replacing Selected Topics with Permanent number; already listed in program
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? This course is offered as an elective for the Metabolic & Nutritional Medicine concentration in the Medical Sciences masters and would serve approximately 25-30 students per year.
  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times? Yes, 1 time
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) All the faculty involved with the course are experienced lecturers with either M.D. or Ph.D. degrees, or both.
  29. Objectives: The objectives of this course include: Developing an understanding of the fundamental biology of the cardiovascular system. Understanding the differences between various components of the cardiovascular system. Discussing various pathophysiological changes that occur in the cardiovascular system. Comparison of the different types of treatment of chronic heart disease. Discuss of the diagnosis and treatment of hypertension. Compareing and contrasting the various potential therapeutic agents used to treat chronic heart disease. Discussing selected case studies of chronic heart disease.
  30. Learning Outcomes: At the completion of this course, participants will be able to:

    • Understand, review and apply in clinical practice the concepts of vascular biology.

    • Understand, review and apply to patient care nutrition, nutritional supplements, exercise and weight management related to vascular biology.

    • Understand, review and discuss the clinical presentation issues and cardiovascular relationships of vascular biology.

    • Understand, review and apply in clinical practice the pathophysiology of vascular aging.

    • Understand, review and apply to patient care nutrition, nutritional supplements, exercise and weight management in the treatment of vascular aging.

    • Understand, review and discuss the clinical presentation and cardiovascular relationships of and vascular aging.

    • Understand, review, discuss, select and apply laboratory testing and new noninvasive diagnostic cardiovascular tests for vascular aging.

    • Understand, review and apply in clinical practice the pathophysiology of hypertension and review and discuss cell energy concepts, mitochondrial function, oxidative stress, inflammation and autoimmune dysfunction as it applies to vascular disease and hypertension.

    • Understand, review and apply to patient care nutrition, nutritional supplements, exercise and weight management in the treatment of hypertension.

    • Understand, review and discuss the clinical presentation and cardiovascular relationships of hypertension and cardiovascular disease.

    • Understand, review, discuss, select and apply laboratory testing and new noninvasive diagnostic cardiovascular tests to identify cardiovascular disease early and select appropriate treatment in hypertension.

  31. Major Topics: Major course topics include:

    Vascular Biology for the Clinician

    Blood vessel structure and endothelial function

    Atherosclerosis

    Assessment of endothelial dysfunction and subclinical vascular disease

    Vascular Aging & Cardiovascular Disease

    Mitochondria and aging

    Mitochondrial biogenesis

    Oxidative stress, inflammation, autoimmune dysfunction and cardiovascular disease

    Vascular cell senescence

    Telomeres and telomere length

    Treatment effects of antihypertensive drugs on arterial compliance

    Integrative Management of Hypertension

    Epidemiology of hypertension

    Pathophysiology of hypertension

    The role of nitric oxide

    Weight loss, exercise and blood pressure

    Nutrient regulation of gene expression

    Treatment of hypertension and a new approach based on vascular biology

  32. Textbooks: • What Your Doctor May Not Tell You About Heart Disease – Grand Central Press – 2012 – Houston, M. –ISBN: 978-1609412548

    • What Your Doctor May Not Tell You About Hypertension – Grand Central Publishing - 2003 – Houston, M - ISBN: 978-0446690843

    • Handbook of Hypertension – Blackwell and Wiley – 2009 - Houston, M - ISBN: 978-1405182508

  33. Course Readings, Online Resources, and Other Purchases: Additional and appropriate readings will be identified and posted on Blackboard.
  34. Student Expectations/Requirements and Grading Policy: 3 case studies or reports (research papers) 15% each, 45% of grade Comprehensive midterm exam 23% of grade Comprehensive final exam 23% of grade 5 webcasts 9% of grade.
  35. Assignments, Exams and Tests: The course requires completion of: 4 unit quizzes (self-assessment) 3 case studies or reports (research papers) Comprehensive midterm exam Comprehensive final exam 5 webcasts.
  36. Attendance Policy: Course Attendance at First Class Meeting – Policy for Graduate Students: For structured courses, 6000 and above, the College/Campus Dean will set the first-day class attendance requirement. Check with the College for specific information. This policy is not applicable to courses in the following categories: Educational Outreach, Open University (TV), FEEDS Program, Community Experiential Learning (CEL), Cooperative Education Training, and courses that do not have regularly scheduled meeting days/times (such as, directed reading/research or study, individual research, thesis, dissertation, internship, practica, etc.). Students are responsible for dropping undesired courses in these categories by the 5th day of classes to avoid fee liability and academic penalty. (See USF Regulation – Registration - 4.0101,

    http://usfweb2.usf.edu/usfgc/ogc%20web/currentreg.htm)

    Attendance Policy for the Observance of Religious Days by Students: In accordance with Sections 1006.53 and 1001.74(10)(g) Florida Statutes and Board of Governors Regulation 6C-6.0115, the University of South Florida (University/USF) has established the following policy regarding religious observances: (http://usfweb2.usf.edu/usfgc/gc_pp/acadaf/gc10-045.htm)

    In the event of an emergency, it may be necessary for USF to suspend normal operations. During this time, USF may opt to continue delivery of instruction through methods that include but are not limited to: Blackboard, Elluminate, Skype, and email messaging and/or an alternate schedule. It’s the responsibility of the student to monitor Blackboard site for each class for course specific communication, and the main USF, College, and department websites, emails, and MoBull messages for important general information.

  37. Policy on Make-up Work: For documented student absences, such as for illness, students will be allowed to make up any missing case reports or exams. Students will be required to abide by USF policy on academic integrity as described in course syllabus.
  38. Program This Course Supports: M.S. in Medical Sciences: Metabolic & Nutritional Medicine concentration
  39. Course Concurrence Information: None


- if you have questions about any of these fields, please contact chinescobb@grad.usf.edu or joe@grad.usf.edu.