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Graduate Course Proposal Form Submission Detail - GMS6XXX
Tracking Number - 2089

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Current Status: Approved, Permanent Archive - 2009-06-03
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Detail Information

  1. Date & Time Submitted: 2009-02-02
  2. Department: Graduate Affairs
  3. College: MD
  4. Budget Account Number: 6108
  5. Contact Person: Michael J. Barber, D.Phil.
  6. Phone: 9749908
  7. Email: mbarber@health.usf.edu
  8. Prefix: GMS
  9. Number: 6XXX
  10. Full Title: Clinical Approaches to Endocrinology
  11. Credit Hours: 3
  12. Section Type: C - Class Lecture (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: Y
  15. Are the credit hours variable?: N
  16. Is this course repeatable?:
  17. If repeatable, how many times?: 0
  18. Abbreviated Title (30 characters maximum): Clinical Endocrinology
  19. Course Online?: -
  20. Percentage Online:
  21. Grading Option: R - Regular
  22. Prerequisites: None
  23. Corequisites: None
  24. Course Description: The course focuses on the function of the human endocrine system and examines factors influencing hormone function and physiological hormone balance. Clinical approaches to achieve hormone homeostasis are emphasized including hormone replacement therapy.

  25. Please briefly explain why it is necessary and/or desirable to add this course: This course is an integral component of the new concentration in Metabolic and Nutritional Medicine that is part of the Medical Sciences Master's program in the College of Medicine. The course is designed to develop physician and health-care professional
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? The current CME activity has an enrollment of over 150 at each course presentation. The current level of enrollment is expected to remain unchanged
  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times? This course has not previously been offered as selected topics at USF. Selected components of the course have been previously offered 4 times as part of a continuing medical education program for clinicians
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) All of the faculty involved in the course have terminal doctoral degrees (M.D. or Ph.D.) in disciples relevant to the course material and have extensive graduate teaching experience
  29. Objectives: The course objectives include:

    • Recognizing the hormonal changes that women and men manifest with aging

    • Discussing the functions of estrogen, progesterone, testosterone, DHEA, cortisol, melatonin, pregnenolone and thyroid hormones in the body

    • Describing the structure of the sex hormones and their metabolism

    • Understandingthe intricate web that the hormones are in the body

    • Discussing the benefits and risk(s) of estrogen, progesterone, testosterone, DHEA, pregnenolone, thyroid, and melatonin replacement

    • Recognizing the symptoms of decline or excess of estrogen, progesterone, testosterone, DHEA, cortisol, thyroid hormone, melatonin, and pregnenlone replacement in both men and women

    • Understanding the differences between synthetic and bio-identical hormones

    • Identifing, order and analyze laboratory tests that are pertinent to hormonal function

    • Understanding the function of the adrenal system and its effects on other sex hormones and hormone replacement

    • Discussing the advantages and disadvantages of hormone replacement therapy and initiate therapy in appropriate individuals

    • Reviewing the literature on synthetic and bio-identical hormone replacement

    • Understanding reasons bio-identical hormone replacement should be considered

    • Monitoring treatment, adjust dosages, alleviate side effects of hormone replacement

    • Recognizing the clinical manifestations of hypothyroidism

    • Discussing the factors that cause decrease production of T4, affect 5’diodinase production, cause an inability to convert T4 to T3, and causes associated with decreased T3 or increased reverse T3

    • Learning factors that increase the conversion of T4 to T3

    • Understanding the crucial role that iodine has in the function of the thyroid gland

    • Discussing appropriate treatment(s) for hormone replacement including compounded thyroid medications

  30. Learning Outcomes: Following the successful completion of the course, students will be able to:

    • Recognize the hormonal changes that women and men manifest with aging

    • Discuss the functions of estrogen, progesterone, testosterone, DHEA, cortisol, melatonin, pregnenolone and thyroid hormones in the body

    • Describe the structure of the sex hormones and their metabolism

    • Understand the intricate web that the hormones are in the body

    • Discuss the benefits and risk(s) of estrogen, progesterone, testosterone, DHEA, pregnenolone, thyroid, and melatonin replacement

    • Recognize the symptoms of decline or excess of estrogen, progesterone, testosterone, DHEA, cortisol, thyroid hormone, melatonin, and pregnenlone replacement in both men and women

    • Understand the differences between synthetic and bio-identical hormones

    • Identify, order and analyze laboratory tests that are pertinent to hormonal function

    • Understand the function of the adrenal system and its effects on other sex hormones and hormone replacement

    • Discuss the advantages and disadvantages of hormone replacement therapy and initiate therapy in appropriate individuals

    • Have reviewed the literature on synthetic and bio-identical hormone replacement

    • Understand reasons bio-identical hormone replacement should be considered

    • Monitor treatment, adjust dosages, alleviate side effects of hormone replacement

    • Recognize the clinical manifestations of hypothyroidism

    • Discuss the factors that cause decrease production of T4, affect 5’diodinase production, cause an inability to convert T4 to T3, and causes associated with decreased T3 or increased reverse T3

    • Learn factors that increase the conversion of T4 to T3

    • Understand the crucial role that iodine has in the function of the thyroid gland

    • Discuss appropriate treatment(s) for hormone replacement including compounded thyroid medications

  31. Major Topics: Hormone replacement therapies

    The effects of stress and changes in hormone levels

    Adrenal fatigue and the use of endocrine tests for diagnostic purposes

    Selective review of appropriate endocrinology case studies

    The structure, synthesis and physiological effects of thyroid hormones

    Male menopause and its physiological effects

    Treatment modalities for testosterone deficiencies

    Bioidentical hormone replacement for females

    The structure and properties of major estrogen derivatives

    Developing personalized hormone treatments

    The clinical aspects of thyroid treatments

    Hormone testing in various body fluids

    Comparing and contrasting premenstrual syndrome (PMS) and polycystic ovary syndrome (PCOS)

    The relevance of stem cells in regenerative medicine

    Discussing the symptoms of hypothyroidism and its diagnosis

    Examining the correlation between bio-identical and synthetic hormone replacement and breast cancer risk

    Describing the facilities available and process for compounded pharmaceutical production

  32. Textbooks: Smith, P., “HRT: The Answers”. Traverse City, MI: Healthy Living Books, 2008.

    Smith, P., What You Must Know About Women’s Hormones. New York: Square One Publishing, 2008.

    Wilson, J., “Adrenal Fatigue”. Petaluma, CA: Smart Publications. 2001.

  33. Course Readings, Online Resources, and Other Purchases:
  34. Student Expectations/Requirements and Grading Policy:
  35. Assignments, Exams and Tests:
  36. Attendance Policy:
  37. Policy on Make-up Work:
  38. Program This Course Supports:
  39. Course Concurrence Information:


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