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Graduate Course Proposal Form Submission Detail - BME6234
Tracking Number - 2074

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Current Status: Approved, Permanent Archive - 2003-05-15
Submission Type:
Course Change Information (for course changes only):

Detail Information

  1. Date & Time Submitted: 2003-05-16
  2. Department: Chemical Engineering
  3. College: EN
  4. Budget Account Number: 210700000
  5. Contact Person: Michael VanAuker, William Lee
  6. Phone: 9743186
  7. Email:
  8. Prefix: BME
  9. Number: 6234
  10. Full Title: Biomedical Fluids and Cardiovascular Engineering
  11. Credit Hours: 3
  12. Section Type: C - Class Lecture (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: N
  15. Are the credit hours variable?: N
  16. Is this course repeatable?:
  17. If repeatable, how many times?: 0
  18. Abbreviated Title (30 characters maximum): Biomedical Fluids
  19. Course Online?: -
  20. Percentage Online:
  21. Grading Option: R - Regular
  22. Prerequisites: Graduate standing in engineering or CI
  23. Corequisites: n/a
  24. Course Description: Roles of mechanics & transport phenomena in pathology, diagnosis & treatment of cardiovascular disease. Intro to methods for assessing hemodynamics & cardiovascular health -Doppler echocardiography & MRI. Cardiovascular devices. Open to nonmajors.

  25. Please briefly explain why it is necessary and/or desirable to add this course: x
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? x
  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times? x
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) x
  29. Objectives: Three main topics will be covered in this class. First, the roles of mechanics and biotransport phenomena in the development, diagnosis, and treatment of cardiovascular disease will be explored. The mechanical behavior of the cardiovascular system will be explored in a quantitative manner. Correlations will be made between function and underlying structural and cellular processes, both for normal and pathological states. Second, invasive and noninvasive methods for assessing hemodynamics and evaluating cardiovascular health will be covered. Lastly, design issues including mechanical function and biocompatibility issues relevant to a variety of cardiovascular devices will be discussed
  30. Learning Outcomes: The students should be able to:1. Develop models of physiologic pressure/flow relationships.2. Cite examples of how biomechanics, fluid mechanics, and transport phenomena affect development, diagnosis, and treatment of disease. 3. Describe invasive and noninvasive methods for assessing cardiovascular health. 4. Describe how the three “M”s (medicine, mechanics, and materials) affect medical device design.
  31. Major Topics: · Anatomy and physiology of the cardiovascular system.· Introduction to blood rheology, including non-Newtonian fluid models.· Equations of motion for pulsatile flow systems, including analytical and numerical methods.· Models of cardiac mechanics and heart valve motion· Wave propagation in the arterial system · Microvascular flow · Invasive and non-invasive flow, velocity, and pressure measurements · The relevance of fluid mechanics to heart disease, atherosclerosis, and hypertension· Design issues for devices such as extracorporeal circuits, prosthetic valves, catheters, stents and cardiac assist devices.
  32. Textbooks: McDonald’s Blood Flow in Arteries: Theoretical, Experimental and Clinical Principles, 4th edition, by Nichols, O’Rourke, Hartley, and McDonald. Oxford University Press (1998).Biomechanics: Circulation, 2nd edition, by Y.C. Fung. Springer-Verlag (1997).Biomaterials Science, Ratner, Hoffman, Schoen and Lemons, eds. Academic Press (1996).Intra- and Extracorporeal Cardiovascular Fluid Dynamics, Vol. 1: General Principles in Application. P. Verdonck, ed. Computational Mechanics Publications (1998).Advanced Engineering Mathematics, 5th edition, by Erwin Kreyszig. John Wiley and Sons (1983).Selected
  33. Course Readings, Online Resources, and Other Purchases:
  34. Student Expectations/Requirements and Grading Policy:
  35. Assignments, Exams and Tests:
  36. Attendance Policy:
  37. Policy on Make-up Work:
  38. Program This Course Supports:
  39. Course Concurrence Information:

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