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Graduate Course Proposal Form Submission Detail - GMS6461
Tracking Number - 2040

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Current Status: Approved, Permanent Archive - 2003-12-05
Submission Type:
Course Change Information (for course changes only):

Detail Information

  1. Date & Time Submitted: 2003-09-11
  2. Department: Medical Science
  3. College: MD
  4. Budget Account Number: 6112-000-20
  5. Contact Person: Eric Bennett
  6. Phone: 9741545
  7. Email:
  8. Prefix: GMS
  9. Number: 6461
  10. Full Title: Systems Physiology and Pharmacology
  11. Credit Hours: 5
  12. Section Type: C - Class Lecture (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: N
  15. Are the credit hours variable?: N
  16. Is this course repeatable?:
  17. If repeatable, how many times?: 0
  18. Abbreviated Title (30 characters maximum): Physiology/Pharmacology
  19. Course Online?: -
  20. Percentage Online:
  21. Grading Option: R - Regular
  22. Prerequisites: GMS 6001 OR equivalent Cell and Molecular Biology course OR Instructor approval
  23. Corequisites: None required - recommend Graduate Neuroscience (GMS 6020)
  24. Course Description: This course will serve as an introduction into human physiology and pharmacology, emphasizing systemic function. The course is not restricted to majors, and is not repeatable.

  25. Please briefly explain why it is necessary and/or desirable to add this course: This course is designed to teach basic systems Physiology and Pharmacology, integrating fundamental information about normal function with the basic mechanisms of therapeutics used to correct (overcome) dysfunctions. Currently, no graduate level systems
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? This course will be required for all Physiology and Pharmacology graduate students in the Spring semester of their first year. In addition, this course will be accessible to all COM graduate students, College of Public Health, Nursing, Arts and Sciences, and Engineering graduate students, Cancer Biology graduate students, as well as advanced undergraduates from all Colleges.
  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times? NO
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) All instructors have M.D. and/or Ph.D. degrees in a biomedical science.
  29. Objectives: This course will provide an introduction into human physiology and pharmacology, with an emphasis on systemic function. The course is designed to integrate fundamental information about normal function with the basic mechanisms of therapeutics used to correct (overcome) dysfunctions.
  30. Learning Outcomes: By the end of the course, the student will be familiar with the following: 1) The basic mechanism by which all major systems of the body function, 2) The principles of therapeutics including pharmacokinetics and pharmacodynamics, and 3) The basic mechanisms of therapeutics.
  31. Major Topics: Topics that will be covered include the following:

    1. Pharmacodynamics

    2. Pharmacokinetics

    3. Cardiac Output/Stroke volume

    4. Mechanism of muscle contraction and excitation/contraction coupling

    5. Muscular Dystrophy/skeletal muscle disorders

    6. Neuromuscular blockers

    7. Energy of heart & muscle

    8. Control of heart rate and cardiac action potentials

    9. Arrhythmias (mechanisms and drug management)

    10. Transgenic models of CV disease

    11. Hemodynamics

    12. Antihyperlipidemia & dyslipidemia

    13. Anticoagulants and thrombolytics

    14. Biomechanical properties of blood vessels

    15. Microcirculation

    16. Regulation blood pressure

    17. Genetics of vascular disease

    18. Vasodilators

    19. Adrenergic pharmacology

    20. Fluids

    21. Renal Physiology

    22. Renal hormones

    23. Acid base balance

    24. Molecular basis of kidney disease

    25. Diuretics

    26. Vasoactive peptides

    27. Pharmacology of hypertension

    28. Drug treatment of congestive heart failure

    29. Cardiovascular gene therapy

    30. Mechanics of Breathing

    31. Pulmonary circulation/diffusion

    32. O2 and CO2 transport/ ventilation/perfusion matching

    33. Neural control of ventilation

    34. Pharmacology of COPD and asthma

    35. Hypothalamus & Pituitary, Growth Hormone

    36. Adrenal Physiology

    37. Endocrine pancreas

    38. Thyroid, Calcium

    39. Male and Female Endocrinology

    40. Adrenal steroids

    41. Thyroid drugs

    42. Antidiabetic drugs

    43. Sex steroids

    44. Regulation and function of the GI tract

    45. Physiology and pharmacology of inhibition/stimulation of acid secretion

    46. Physiology and pharmacology of motility

  32. Textbooks: "Physiology," 5th ed., by Berne et al.

    "Basic & Clinical Pharmacology," 8th ed., by Katzung

  33. Course Readings, Online Resources, and Other Purchases:
  34. Student Expectations/Requirements and Grading Policy:
  35. Assignments, Exams and Tests:
  36. Attendance Policy:
  37. Policy on Make-up Work:
  38. Program This Course Supports:
  39. Course Concurrence Information:

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