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Graduate Course Proposal Form Submission Detail - GMS6841

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Current Status: Approved, Permanent Archive - 2007-02-14
Submission Type:
Course Change Information (for course changes only):

  1. Department and Contact Information

    Tracking Number Date & Time Submitted
    1735 2006-10-18
    Department College Budget Account Number
    USF Health Office of Research MD 600105
    Contact Person Phone Email
    Sandra Anderson 45566

  2. Course Information

    Prefix Number Full Title
    GMS 6841 Fundamentals of Translational Research

    Is the course title variable? N
    Is a permit required for registration? N
    Are the credit hours variable? N
    Is this course repeatable?
    If repeatable, how many times? 0

    Credit Hours Section Type Grading Option
    1 C - Class Lecture (Primarily) R - Regular
    Abbreviated Title (30 characters maximum)
    Translational Research Basics
    Course Online? Percentage Online


    Postdoctoral status, doctoral student in Medical Sciences


    Permission of Instructor

    Course Description

    Introduction to the interface between clinical and basic research. How to include basic research hypotheses in the design of clinical studies to advance knowledge in applying bsic/clinical research to patient care. Instructor permission. Not repeatable.

  3. Justification

    A. Please briefly explain why it is necessary and/or desirable to add this course.

    This course has been developed to meet the requirements of a National Institutes of Health-supported program for training health professionals withthe knowledge and skills necessary to conduct academic patient-oriented research. The course is required to

    B. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service?

    No course currently exists to teach patient-oriented researchers about the value to advancing knowledge in patient care inherent in collaborative interactions with basic researchers to develop productive research studies that translate into more effective interventions in patient care. This course is part of a required sequence to complete a concentration in Clinical and Translational Research in the Master of Science in Medical Sciences degree program in the College of Medicine. Upon consultation with the course instructor, Medical Sciences doctoral students, and other postdoctoral individuals in the medical school may enroll.

    C. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times?

    No. It is on the schedule as a Special Topics course for Spring 2007.

    D. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.)

    Minimum qualifications include either a PhD and/or MD and experience in translational research related to patient-oriented studies.

  4. Other Course Information

    A. Objectives

    1. Introduce students to how research questions addressed in the basic science lab can lead to development of clinically relevant diagnostic, therapeutic and population-based studies. 2. Introduce students to how laboratory correlates can be incorporated into and strengthen a clinical study. 3. Introduce students to many of the common basic laboratory techniques which can be utilized to address research questions in primarily clinical and translational studies. 4. Demonstrate how addition of basic research hypotheses to clinical research hypotheses can lead to higher quality, more competitive clinical/translational research grant applications.

    B. Learning Outcomes

    Upon completion of the course, students will be able to discuss strategies for identifying basic science collaborators, list possible basic science contributions to clinical research studies, name basic laboratory tests that can provide additional information to help explain clinical research results, outline ways addition of basic research hypotheses can strengthen clinical/translational research grant applications.

    C. Major Topics

    What does it mean to be a translational researcher? Strategies for clinical researchers to establish productive, collaborative relationships with basic science investigators. How to utilize core facilities for basic research techniques to address basic science questions in primarily clinical research studies. Assessment of pharmacokinetics, pharmacodynamics, and drug toxicity in clinical trials. Immunologic endpoints in clinical/translational research studies. Collaboration with biomedical engineers in clinical research. Molecular correlates of response and toxicity. Correlations between biologic response and clinical response in therapeutic studies. Pharmacogenomics. Genetic epidemiology.

    D. Textbooks

    Materials to be distributed in class.

    E. Course Readings, Online Resources, and Other Purchases

    F. Student Expectations/Requirements and Grading Policy

    G. Assignments, Exams and Tests

    H. Attendance Policy

    I. Policy on Make-up Work

    J. Program This Course Supports

  5. Course Concurrence Information

- if you have questions about any of these fields, please contact or