Graduate Studies Reports Access

Graduate Course Proposal Form Submission Detail - BCH6420
Tracking Number - 1650

Edit function not enabled for this course.

Current Status: Approved, Permanent Archive - 2007-06-28
Submission Type:
Course Change Information (for course changes only):

Detail Information

  1. Date & Time Submitted: 2007-05-01
  2. Department: Molecular Medicine
  3. College: MD
  4. Budget Account Number: 6111
  5. Contact Person: Michael J. Barber, D.Phil.
  6. Phone: 9749702
  7. Email:
  8. Prefix: BCH
  9. Number: 6420
  10. Full Title: Clinical Correlations in Molecular Medicine
  11. Credit Hours: 3
  12. Section Type: C - Class Lecture (Primarily)
  13. Is the course title variable?: N
  14. Is a permit required for registration?: Y
  15. Are the credit hours variable?: N
  16. Is this course repeatable?:
  17. If repeatable, how many times?: 0
  18. Abbreviated Title (30 characters maximum): Clinical Correlations in Molec
  19. Course Online?: -
  20. Percentage Online:
  21. Grading Option: R - Regular
  22. Prerequisites: GMS 6200 or GMS 6001
  23. Corequisites: None
  24. Course Description: The course concentrates on molecular medicine and focuses on several disease conditions that provide an “in-depth” understanding of how changes in cellular structure/function and metabolic pathway regulation can result in diseases and their therapy.

  25. Please briefly explain why it is necessary and/or desirable to add this course: This course is part of the new Molecular Medicine concentration in the MS in Medical Sciences program and will also comprise part of the new MS concentration in Health Sciences that is being developed by the College of Medicine. The course utilizes a "pro
  26. What is the need or demand for this course? (Indicate if this course is part of a required sequence in the major.) What other programs would this course service? This course is a requirement for the new Molecular Medicine concentration in the MS in Medical Sciences program and will also comprise part of the proposed new Master's concentration in Health Sciences. We currently have 40 students enrolled in the Molecular Medicine concentration this year and anticipate an enrollment of approximately 50 students per year in later years. This course could also be used by MS and doctoral students in other colleges interested in clinical correlations in molecular medicine. Given the interest in this field, we anticipate there could be high demand by Medical Science and Biology graduate students.
  27. Has this course been offered as Selected Topics/Experimental Topics course? If yes, how many times? Yes, this course is currently being offered during the Summer semester of 2007
  28. What qualifications for training and/or experience are necessary to teach this course? (List minimum qualifications for the instructor.) Instructors for this course must possess a Ph.D. degree in biochemistry, molecular biology or a related discipline and have experience of teaching these topics described in this course to both medical students and graduate students. The current instructor in this course, Michael J. Barber, D.Phil., is a senior faculty member in the Department of Molecular Medicine in College of Medicine with a doctoral degree in Biochemistry and a fully-credentialed member of the College’s Graduate Faculty. He has over 23 years of experience in teaching and research at both the undergraduate and graduate levels at the University of South Florida in the topics described in the course synopsis.
  29. Objectives: The course objectives include:

    1. Describing the principal alterations in cellular function that result in a variety of diseases at the molecular level.

    2. Describing the major diagnostic steps that were utilized to define the disease process.

    3. Examining potential treatments and therapies that could be used to cure or ameliorate the various diseases.

    4. Illustrating if specific groups within the general population are at risk for the various cellular defects and the mode of inheritance for those diseases that are genetically based.

    5. Highlighting the role of basic science in guiding diagnosis, management, therapeutics, and disease prevention.

  30. Learning Outcomes: At the conclusion of this course, students will be able to discuss and describe the following features of all the diseases covered in the course:

    1. discuss the pathophysiology, incidence/prevalence and mortality/morbidity associated with the disease, along with the race, sex, and age range of persons typically affected

    2. recognize the typical clinical presentation, including common symptoms and physical examination findings

    3. generate an appropriate differential diagnosis

    4. choose laboratory, imaging, and diagnostic studies, tests, and procedures helpful in confirming the diagnosis and recognize associated histologic findings

    5. describe proper medical care and recommend appropriate treatments

    6. list medications useful in treatment

    7. discuss potential complications and prognosis

  31. Major Topics: Major course topics include Sickle Cell Anemia, a1-Antitrypsin Deficiency, Cardiac Troponin and Myocardial Infarction, Mitochondrial Encephalopathy, Neonatal Hypoglycemia, Inborn Errors of Urea Synthesis,

    Phenylketonuria, Neonatal Hyperbilirubinemia, Vitamin B12 Deficiency, Jaundice and Gall Stone Disease, Lead Poisoning

    and Chronic Granulomatous Disease

  32. Textbooks: The course requires the following textbook: “Clinical Studies in Medical Biochemistry” (Glew, R.H. and Rosenthal, M.D.), 3rd Ed., Oxford University Press, 2006.

    ISBN-13: 978-0195176889

  33. Course Readings, Online Resources, and Other Purchases:
  34. Student Expectations/Requirements and Grading Policy:
  35. Assignments, Exams and Tests:
  36. Attendance Policy:
  37. Policy on Make-up Work:
  38. Program This Course Supports:
  39. Course Concurrence Information:

- if you have questions about any of these fields, please contact or